Figure 7 from Nanoparticulate Immunoactive Complex for Local Chemoimmunotherapy: From Murine Models to Pilot Canine Study

Authors:
Open Access
Publisher website
Google Scholar
Abstract
Histology of companion dog tumors before and after IMAX treatment. A, Histology of dog RV soft tissue sarcoma. Left, perivascular lymphocytic infiltration (▲). Middle, lack of identifiable tumor cells and marked leukocytic (primarily neutrophils) infiltration with mitotically active giant cells (→). Right, perivascular lymphocytic infiltration (▲) and blue extracellular and intracellular granular materials (inset) located mainly at the tumor periphery. B, Histology of dog SP soft tissue sarcoma. Right, marked intratumoral lymphocytic infiltration (▲). C, Histology of dog CL mammary carcinomas. Ca, caudal mammary gland; Cr, cranial mammary gland. D, Histology of dog BM mammary carcinoma. Right, some areas of the tumor 3 weeks after the second treatment include both malignant epithelial (*) component and malignant mesenchymal component with osteoid (▲), characteristic of carcinosarcoma. Scale bars, 100 μm.