Clinical Results of Topography-based Customized Ablations for Myopia and Myopic Astigmatism

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Abstract
PURPOSE: To evaluate clinical outcomes after primary treatments for myopia and myopic astigmatism with topography-based ablation profiles on the Allegretto Wave Eye-Q platform (Alcon Laboratories Inc). METHODS: Records of patients who underwent topography-guided, Q-adjusted LASIK were retrieved and analyzed. Patients with mean refractive spherical equivalent up to −16.00 diopters (D) and cylindrical errors up to 6.00 D were included (2051 eyes). Refractive outcomes and visual acuities were analyzed preoperatively and 3 months postoperatively. RESULTS: Manifest spherical refractive error decreased from −5.05±2.33 to +0.04±0.35 D. Manifest cylindrical refractive error decreased from 0.83±0.75 to 0.23±0.22 D. At 3 months postoperatively, 86.1% (1766 eyes) had a spherical equivalent refraction within ±0.50 D of targeted refraction. The number of eyes with uncorrected distance visual acuity of 20/16 and 20/20 was 851 (41.5%) and 1495 (72.9%), respectively. At 3 months, 0.10% (2 eyes) lost more than 2 lines of corrected distance visual acuity and a loss of 2 lines occurred in 0.24% (5 eyes). All patients who lost lines of visual acuity were found to have corneal erosions related to dryness and recovered vision on further follow-up. CONCLUSIONS: The results of this retrospective study demonstrate refractive predictability, efficacy, and safety comparable to other treatment modalities such as wavefront-optimized and wavefront-guided treatments. Results are also similar to those reported with other topography-guided systems.

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