Meningeal involvement in early stage chronic lymphocytic leukemia
Authors:
Abstract
Two patients with early stage chronic lymphocytic leukemia were found to have meningeal involvement. The diagnosis was confirmed by cerebral spinal fluid cytology in the first patient and by flow cytometric analysis in the second patient. Both patients responded well to intrathecal chemotherapy and cranial irradiation. Central nervous system infiltration by tumor cells has rarely been described in chronic lymphocytic leukemia but must be considered in all patients regardless of stage who present with lethargy, dementia, or focal neurologic signs. Cancer 59:798‐800, 1987.Keywords
This publication has 7 references indexed in Scilit:
- Central nervous system involvement in non-Hodgkin's lymphoma: An analysis of 105 casesCancer, 1982
- Meningeal leukemia complicating chronic lymphocytic leukemiaCancer, 1981
- Natural history of central nervous system acute leukemia in adultsCancer, 1981
- Two populations of Ia-like molecules on a human B cell line.The Journal of Immunology, 1980
- CNS involvement in the non-hodgkin's lymphomasCancer, 1980
- Spinal cord involvement in chronic lymphocytic leukemiaCancer, 1979
- Clinical staging of chronic lymphocytic leukemiaBlood, 1975