Chitosan‐Alginate Complex Coacervate Capsules: Effects of Calcium Chloride, Plasticizers, and Polyelectrolytes on Mechanical Stability
Authors:
- 1 June 1988
- journal article
- research article
- Published by Wiley in Biotechnology Progress
- Vol. 4 (2) , 76-81
Abstract
A method has been developed to form capsules with liquid cores where permeability can be modified without sacrificing membrane strength. The capsule is formed by dropwise addition of a 3% chitosan (polycation) solution into a 0.75% alignate (polyanion) solution. The resultant capsule consists of a liquid chitosan core with a hard alginate coating. The addition of CaCl2 to chitosan and glucose to alginate increased capsule strength. The membranes formed were strong enough to require up to 100 Newton during uniaxial compression to burst a 6.4 mm diameter capsule.Keywords
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