Swirling Flow Can Suppress Flow Disturbances in Endovascular Stents: A Numerical Study
Authors:
- Yubo FanYFYubo Fan
- Xiaoyan DengXDXiaoyan Deng
- Zaipin XuZXZaipin Xu
- 1 November 2009
- journal article
- Published by Wolters Kluwer Health in ASAIO Journal
- Vol. 55 (6) , 543-549
Abstract
To test the hypothesis that by intentionally inducing swirling flow in an endovascular stent, hemodynamic performance of the stent can be improved, we numerically analyzed the flow characteristics in a simplified model of a stent within a straight segment of an artery in which swirling flow was introduced intentionally. The study was designed with two purposes: 1) to investigate whether swirling flow is beneficial to suppress flow disturbance in the stent; and 2) to determine the minimum helical strength of the swirling flow required in the design of a swirling flow stent. The numerical simulation showed that the swirling flow indeed reduced the size of the disturbed flow zones, enhanced the average wall shear stress, and lowered oscillatory shear index in the stent, which have been believed to be adverse factors involved in the development of arterial restenosis after stent deployment. The minimum inlet helicity density (or strength) of the swirling flow required was approximately 6.5 m/s(2). Based on the study, it is also believed that a stent with a structure that possesses intrinsic characteristics to automatically induce swirling flow in the stent is better than a stent with a front swirling flow inducer in terms of hemodynamics.Keywords
This publication has 30 references indexed in Scilit:
- Still a future for the bare metal stent?International Journal of Cardiology, 2007
- Circumferential vascular deformation after stent implantation alters wall shear stress evaluated with time-dependent 3D computational fluid dynamics modelsJournal of Applied Physiology, 2005
- Blood Flow in Stented Arteries: A Parametric Comparison of Strut Design Patterns in Three DimensionsJournal of Biomechanical Engineering, 2005
- Sirolimus-Eluting Stents versus Standard Stents in Patients with Stenosis in a Native Coronary ArteryNew England Journal of Medicine, 2003
- Three-Dimensional Computational Fluid Dynamics Modeling of Alterations in Coronary Wall Shear Stress Produced by Stent ImplantationAnnals of Biomedical Engineering, 2003
- Experimental study of laminar blood flow through an artery treated by a stent implantation: characterisation of intra-stent wall shear stressJournal of Biomechanics, 2003
- Focal In-Stent Restenosis Near Step-UpCirculation, 2002
- A Randomized Comparison of a Sirolimus-Eluting Stent with a Standard Stent for Coronary RevascularizationNew England Journal of Medicine, 2002
- Relationship Between Neointimal Thickness and Shear Stress After Wallstent Implantation in Human Coronary ArteriesCirculation, 2001
- Vessel Size and Long-Term Outcome After Coronary Stent PlacementCirculation, 1998