EGFR-targeted drugs and resistance mechanisms in non–small cell lung cancer: Molecular insights and emerging therapeutic strategies
Authors:
- Suleiman Ibrahim MohammadSMSuleiman Ibrahim Mohammad
- Asokan VasudevanAVAsokan Vasudevan
- Tareq Nayef AlRamadnehTATareq Nayef AlRamadneh
- Ihsan K. JasimIJIhsan K. Jasim
- Tushar B. GajjarTGTushar B. Gajjar
- Malathi HanumanthayyaMHMalathi Hanumanthayya
- Sandeep Kumar ShuklaSSSandeep Kumar Shukla
- Navin Kumar TailorNTNavin Kumar Tailor
- Mirza R. BaigMBMirza R. Baig
- Zahraa AbbasZAZahraa Abbas
- 9 November 2026
- journal article
- Published by Springer Nature in DARU Journal of Pharmaceutical Sciences
- Vol. 35 (1)
Abstract
No abstract availableThis publication has 186 references indexed in Scilit:
- Overcoming EGFR‐Mediated Dendritic Cell Dysfunction to Enhance Anti‐tumor Immunity in EGFR‐Mutant NSCLC by Precisely Targeting CD73 With pH‐responsive NanocarriersAdvanced Science, 2025
- A Neovascularization and EGFR Dual‐Targeting Gold Nanotheranostic System for Non‐Small Cell Lung Cancer TreatmentAdvanced Healthcare Materials, 2025
- Update 2025: Management of Non‑Small-Cell Lung CancerLung, 2025
- Liquid biopsy detects genomic drivers in NSCLC without EGFR mutations by single‐plex testing: WJOG13620LCancer Medicine, 2023
- Overcoming AZD9291 Resistance and Metastasis of NSCLC via Ferroptosis and Multitarget Interference by Nanocatalytic Sensitizer Plus AHP‐DRI‐12Small, 2022
- Editorial for “Preoperative MRI‐Based Radiomics of Brain Metastasis to Assess T790M Resistance Mutation After EGFR‐TKI Treatment in NSCLC”Journal of Magnetic Resonance Imaging, 2022
- In vitro and in vivo evaluation of a novel anti-EGFR antibody labeled with 89Zr and 177LuJournal of Radioanalytical and Nuclear Chemistry, 2022
- EGFR mutation analysis on circulating free DNA in NSCLC: a single-center experienceJournal of Cancer Research and Clinical Oncology, 2021
- EGFR‐targeted therapy alters the tumor microenvironment in EGFR‐driven lung tumors: Implications for combination therapiesInternational Journal of Cancer, 2019
- Acquired Resistance ofEGFR-Mutant Lung Cancer to a T790M-Specific EGFR InhibitorJAMA Oncology, 2015