Tareq Nayef AlRamadneh
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Tareq Nayef AlRamadneh has a total of 24 co-authors. Here are the top co-authors by number of shared publications:
- Rajesha Javaraiah
Department of Biochemistry, Yuvaraja’s College, University of Mysore Mysuru, Karnataka 570005, India
3 shared publications Amir Abdul Kadhim
2 shared publicationsDivya Singhal
2 shared publicationsDjamila Polatova
2 shared publicationsJasur Rizaev
2 shared publicationsK.V. Jamuna
2 shared publications
Latest Publications
- Open Access
- 30 October 2026
- Published by Elsevier in Cancer Treatment and Research Communications
- Vol. 49
ceRNA-mediated regulation of ferroptosis in the lung cancer tumor microenvironment: molecular mechanisms, therapeutic opportunities, and research gaps
- 30 October 2026
- Published by Elsevier in Cancer Treatment and Research Communications
- Vol. 49
Open AccessceRNA-mediated regulation of ferroptosis in the lung cancer tumor microenvironment: molecular mechanisms, therapeutic opportunities, and research gaps
- Open Access
- 19 October 2026
- Published by Elsevier in Cancer Treatment and Research Communications
- Vol. 49
Non-coding RNA networks remodeling metastatic signaling in the lung cancer microenvironment: a focus on TGF-β signaling and its crosstalk with Wnt/β-catenin, HIF, Notch, integrin, and CXCL12/CXCR4 pathways
- 19 October 2026
- Published by Elsevier in Cancer Treatment and Research Communications
- Vol. 49
Open AccessNon-coding RNA networks remodeling metastatic signaling in the lung cancer microenvironment: a focus on TGF-β signaling and its crosstalk with Wnt/β-catenin, HIF, Notch, integrin, and CXCL12/CXCR4 pathways
- 9 March 2022
- Published by Taylor & Francis in Drug and Chemical Toxicology
- Vol. 45 (5) , 2221-2232
Synergistic hepatoprotective effects of ω-3 and ω-6 fatty acids from Indian flax and sesame seed oils against CCl 4 -induced oxidative stress-mediated liver damage in rats
Flaxseed (FS) and sesame seed (SS) are traditional and functional foods in traditional Indian medicine for treating various disorders. The present study investigated the hepatoprotective effects of bioactive-fatty acids (FAs) from FS and SS against carbon tetrachloride (CCl4)-induced hepatic damage in rats. Pre and post-treatments for 28 consecutive days significantly increased the activities of in vivo antioxidant enzymes such as catalase (CAT), superoxide dismutase (SOD), and peroxidase (POX), whereas, lipid peroxidation (LPO) activity was markedly decreased in a dose-dependent manner in liver and kidneys. A significant reduction was observed in the hematological parameters like aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), and total bilirubin in the serum of post-treated animals compared to the negative control. The results were confirmed histopathologically. The results suggested that the ω-3 and ω-6 FAs from flaxseed oil (FSO) and sesame seed oil (SSO), respectively, showed potential synergistic hepatoprotective and antioxidant effects that were mediated mainly by ω-3 and ω-6 FAs present in the respective seed oils. Graphical Abstract
- 9 March 2022
- Published by Taylor & Francis in Drug and Chemical Toxicology
- Vol. 45 (5) , 2221-2232
Synergistic hepatoprotective effects of ω-3 and ω-6 fatty acids from Indian flax and sesame seed oils against CCl 4 -induced oxidative stress-mediated liver damage in rats
Flaxseed (FS) and sesame seed (SS) are traditional and functional foods in traditional Indian medicine for treating various disorders. The present study investigated the hepatoprotective effects of bioactive-fatty acids (FAs) from FS and SS against carbon tetrachloride (CCl4)-induced hepatic damage in rats. Pre and post-treatments for 28 consecutive days significantly increased the activities of in vivo antioxidant enzymes such as catalase (CAT), superoxide dismutase (SOD), and peroxidase (POX), whereas, lipid peroxidation (LPO) activity was markedly decreased in a dose-dependent manner in liver and kidneys. A significant reduction was observed in the hematological parameters like aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), and total bilirubin in the serum of post-treated animals compared to the negative control. The results were confirmed histopathologically. The results suggested that the ω-3 and ω-6 FAs from flaxseed oil (FSO) and sesame seed oil (SSO), respectively, showed potential synergistic hepatoprotective and antioxidant effects that were mediated mainly by ω-3 and ω-6 FAs present in the respective seed oils. Graphical Abstract
- 1 September 2020
- Published by Elsevier in Journal of Trace Elements in Medicine and Biology
- Vol. 61, 126552
Secoisolariciresinol diglucoside protects against cadmium-induced oxidative stress-mediated renal toxicity in rats
- 1 September 2020
- Published by Elsevier in Journal of Trace Elements in Medicine and Biology
- Vol. 61, 126552
Secoisolariciresinol diglucoside protects against cadmium-induced oxidative stress-mediated renal toxicity in rats
- 6 September 2019
- Published by Springer Nature in Molecular Biology Reports
- Vol. 46 (6) , 6171-6179
Evaluation of protective efficacy of flaxseed lignan-Secoisolariciresinol diglucoside against mercuric chloride-induced nephrotoxicity in rats
The toxicity of heavy metals such as mercury (Hg) in humans and animals is well documented. The kidney is the primary deposition site of inorganic-Hg and target organ of its toxicity. The present study investigated the protective efficacy of flaxseed lignan-Secoisolariciresinol diglucoside (SDG) on nephrotoxicity induced by mercuric chloride (HgCl2). Rats were intraperitoneally injected with HgCl2 (2 mg/kg/day) and renal toxicity was induced. Subcutaneous administration of rats with SDG (5 mg/kg/day) as a pre-treatment caused a significant reversal of HgCl2 induced increase in blood urea, creatinine, glutathione s-transferase and catalase (CAT). On the other hand, administration of SDG with HgCl2 restored normal levels of albumin and superoxide dismutase (SOD). Histological examination of kidneys confirmed that pre-treatment of SDG before HgCl2 administration significantly reduced its pathological effects. Thus, the results of the present investigation suggest that SDG can significantly reduce renal damage, serum and tissue biochemical profiles caused by HgCl2 induced nephrotoxicity. Hence, SDG may be recommended for clinical trials in the treatment of kidney disorders caused by exposure to Hg.
- 6 September 2019
- Published by Springer Nature in Molecular Biology Reports
- Vol. 46 (6) , 6171-6179
Evaluation of protective efficacy of flaxseed lignan-Secoisolariciresinol diglucoside against mercuric chloride-induced nephrotoxicity in rats
The toxicity of heavy metals such as mercury (Hg) in humans and animals is well documented. The kidney is the primary deposition site of inorganic-Hg and target organ of its toxicity. The present study investigated the protective efficacy of flaxseed lignan-Secoisolariciresinol diglucoside (SDG) on nephrotoxicity induced by mercuric chloride (HgCl2). Rats were intraperitoneally injected with HgCl2 (2 mg/kg/day) and renal toxicity was induced. Subcutaneous administration of rats with SDG (5 mg/kg/day) as a pre-treatment caused a significant reversal of HgCl2 induced increase in blood urea, creatinine, glutathione s-transferase and catalase (CAT). On the other hand, administration of SDG with HgCl2 restored normal levels of albumin and superoxide dismutase (SOD). Histological examination of kidneys confirmed that pre-treatment of SDG before HgCl2 administration significantly reduced its pathological effects. Thus, the results of the present investigation suggest that SDG can significantly reduce renal damage, serum and tissue biochemical profiles caused by HgCl2 induced nephrotoxicity. Hence, SDG may be recommended for clinical trials in the treatment of kidney disorders caused by exposure to Hg.