Supplemental Figure 2 from Defective DNA Damage Response Is a Targetable Therapeutic Vulnerability in ESR1-Mutant Breast Cancer

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Abstract
ESR1m defective RSR signature shows prognostic association with disease specific survival (DSS) in the METABRIC ER+ breast cancer cohort Kaplan-Meier plot of high (top 50%) versus low (bottom 50%) of patients expressing the ESR1 mutant defective replication stress response signature in the METABRIC ER+ patient cohort. P-values were determined utilizing the log-rank test.