EVIDENCE FOR AND ROLE OF THE DIMETHYLAMINO GROUP IN TAMOXIFEN DNA INTERCALATION IN INTACT CHINESE HAMSTER V79 CELLS
- 1 January 2002
- journal article
- Published by Taylor & Francis in Drug and Chemical Toxicology
- Vol. 25 (4) , 473-479
Abstract
The in vitro and in vivo genotoxicity of tamoxifen is well documented but the underlying mechanism of this genotoxicity is only poorly understood. Tamoxifen is known to form adducts with DNA and it...Keywords
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