Palladium‐Catalyzed Regioselective Cyclocarbonylation of N‐(3‐Phenylprop‐2‐ynyl)anilines with Carbon Monoxide and Alcohols for the Synthesis of Quinoline‐3‐carboxylic Esters
Authors:
- 5 July 2018
- journal article
- research article
- Published by Wiley in Asian Journal of Organic Chemistry
- Vol. 7 (8) , 1605-1608
Abstract
A convenient palladium‐catalyzed regioselective cyclocarbonylation of N‐(3‐phenylprop‐2‐ynyl)anilines with carbon monoxide and alcohols has been developed. This methodology provides a simple and practical approach to various quinoline‐3‐carboxylic esters in good yields with high atom efficiency.Keywords
Funding Information
- National Natural Science Foundation of China (21472147, 21622203)
This publication has 55 references indexed in Scilit:
- Modular Access to Azepines by Directed Carbonylative C–C Bond Activation of AminocyclopropanesJournal of the American Chemical Society, 2018
- Carbonylation Access to Phthalimides Using Self-Sufficient Directing Group and NucleophileThe Journal of Organic Chemistry, 2017
- Non-noble metal-catalysed carbonylative transformationsChemical Society Reviews, 2017
- Markovnikov‐Selective Palladium Catalyst for Carbonylation of Alkynes with HeteroarenesAngewandte Chemie, 2017
- Markovnikov‐Selective Palladium Catalyst for Carbonylation of Alkynes with HeteroarenesAngewandte Chemie International Edition, 2017
- Cobalt-Catalyzed Intramolecular Oxidative C(sp3)–H/N–H Carbonylation of Aliphatic AmidesOrganic Letters, 2017
- Ligand- and Additive-Controlled Pd-Catalyzed Aminocarbonylation of Alkynes with Aminophenols: Highly Chemo- and Regioselective Synthesis of α,β-Unsaturated AmidesACS Catalysis, 2017
- Copper-Catalyzed Carbonylative Synthesis of Aliphatic Amides from Alkanes and Primary Amines via C(sp3)–H Bond ActivationACS Catalysis, 2016
- Synthesis of Indolizine Derivatives by Pd-Catalyzed Oxidative CarbonylationOrganic Letters, 2015
- Palladium-Catalyzed Carbonylative Cyclization/Arylation Cascade for 2-Aroylindolizine SynthesisOrganic Letters, 2012