Enzymatic Sywmesis of Dideoxyribonucleosides
Authors:
- 1 January 1991
- journal article
- oral communications
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 10 (1) , 465-468
Abstract
Two N-deoxyribosyltransferases from Lactobacillus leichmanii have been purified and the amino acids involved in the catalysis of the transfer reaction determined. A crude mixture of the transferases have been used to synthesise a purine 2′,5′-dideoxynucleoside in high yield.Keywords
This publication has 4 references indexed in Scilit:
- The stereoselective enzymatic synthesis of 9-β-d-2′-deoxyribofuranosyl 1-deazapurineNucleic Acids Research, 1989
- Adenosine Inhibition of Calmodulin‐Sensitive Adenylate Cyclase from Bovine Cerebral CortexJournal of Neurochemistry, 1986
- Imidazo[4,5-c]pyridines (3-deazapurines) and their nucleosides as immunosuppressive and antiinflammatory agentsJournal of Medicinal Chemistry, 1986
- Chemical Transformations of the Sugar Moiety of Nucleosides1979