The Kondrat’eva Reaction in Flow: Direct Access to Annulated Pyridines
- 27 June 2013
- journal article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 15 (14) , 3550-3553
Abstract
A continuous flow inverse-electron-demand Kondrat'eva reaction has been developed that provides direct access to cycloalka[c]pyridines from unactivated oxazoles and cycloalkenes. Annulated pyridines obtained by this one-step process are valuable scaffolds for medicinal chemistry.Keywords
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