Children with dyskinetic cerebral palsy are severely affected as compared to bilateral spastic cerebral palsy

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Abstract
Aim: We aimed at describing clinical findings in children with dyskinetic as compared to bilateral spastic cerebral palsy (CP).Methods: Data were extracted from the Danish nationwideCPregister. Participants were born in 1999–2007 and were 5–6 years at ascertainment.Results: The total number ofCPcases was 1165 of which 92 had dyskinetic and 540 bilateral spasticCP. Prevalence of dyskineticCPwas 0.16 per 1000 live births. In participants with dyskinetic compared to bilateral spasticCP, there was more frequently an Apgar level less than five at five minutes (22.7% vs. 11.2%) and neonatal seizures (43.5% vs. 28.5%), but less respiratory deficiency, hyperbilirubinaemia and sepsis. Impairment based on gross motor function classification was more severe in dyskineticCP(levelIII–V 90.0% vs. 66.0%). In dyskineticCP, there was a high rate of reduced developmental quotient (68.1%), visual impairment (39.3%) and epilepsy (51.6%). Basal ganglia lesions were more prevalent in dyskinetic compared to bilateral spasticCP(27.7% vs. 12.8%).Conclusion: Cases of dyskineticCPhad overlapping clinical features with cases of bilateral spasticCP, but differed significantly in several perinatal risk factors. The children with dyskineticCPhad experienced more peri‐ or neonatal adverse events, and neurodevelopmental impairment was severe.

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