Lamivudine Resistance in Human T-Cell Leukemia Virus Type 1 May Be Due to a Polymorphism at Codon 118 (V→I) of the Reverse Transcriptase

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Abstract
In a recent report, Balestrieri et al. ([1][1]) asserted that the effect of lamivudine (3TC) against human T-cell leukemia virus type 1 (HTLV-1) at therapeutic concentrations is seen mainly on cell proliferation, with little or no direct antiviral effect. These findings are supported by biochemical

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