Early experience with the Micro Plug Set for preterm patent ductus arteriosus closure

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Abstract
Objectives: We intend to describe early experience using a new, commercially available Micro Plug Set for preterm neonate and infant transcatheter patent ductus arteriosus (PDA) occlusion.Background: Transcatheter PDA occlusion in premature neonates and small infants is safe and effective. The procedure is early in its evolution.Methods: Procedural and short‐term outcomes of preterm neonates and infants undergoing transcatheter PDA occlusion with a new, commercially available device were reviewed.Results: Eight preterm neonates and infants born at median 27 weeks gestation (23–36 weeks) underwent transcatheter PDA device closure with the Micro Plug Set. The device is short (2.5 mm) with a range of diameters (3, 4, 5, 6 mm) and delivered through a microcatheter. Procedures were performed at median 41 days of age (12–88 days) and at 1690 g (760–3,310 g). Transvenous PDA device occlusion was performed with fluoroscopic and echocardiography guidance. All procedures were successful with complete PDA occlusion. There were no procedural or short‐term adverse events.Conclusions: Preterm neonate and infant transcatheter PDA device closure with a new, commercially available short and microcatheter delivered device (Micro Plug Set) was safe and effective in a small, early series of patients.

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