Epithalon Inhibits Tumor Growth and Expression of HER-2/neu Oncogene in Breast Tumors in Transgenic Mice Characterized by Accelerated Aging
Authors:
- 1 February 2002
- journal article
- Published by Springer Nature in Bulletin of Experimental Biology and Medicine
- Vol. 133 (2) , 167-170
Abstract
Female transgenic FVB mice carrying breast cancer gene HER-2/neu were monthly injected with Vilon or Epithalon (1 μg subcutaneously for 5 consecutive days) starting from the 2nd month of life....Keywords
This publication has 13 references indexed in Scilit:
- Mutant and genetically modified mice as models for studying the relationship between aging and carcinogenesisMechanisms of Ageing and Development, 2001
- Effect of synthetic thymic and pineal peptides on biomarkers of ageing, survival and spontaneous tumour incidence in female CBA miceMechanisms of Ageing and Development, 2001
- Experimental Studies of the Pineal Gland Preparation Epithalamin2001
- Effect of epitalon on the lifespan increase in Drosophila melanogasterMechanisms of Ageing and Development, 2000
- The age of cancerNature, 2000
- Amplification of the neu/erbB-2 oncogene in a mouse model of mammary tumorigenesisProceedings of the National Academy of Sciences, 2000
- Longevity, genes, and aging: a view provided by a genetic model systemExperimental Gerontology, 1999
- A putative gene causes variability in lifespan among genotypically identical miceNature Genetics, 1998
- Natural and synthetic thymic peptides as therapeutics for immune dysfunctionInternational Journal of Immunopharmacology, 1997
- An activated allele of the c-erbB-2 oncogene impairs kidney and lung function and causes early death of transgenic miceJournal of Cell Biology, 1993