Cloning and complete amino acid sequences of human and murine basement membrane protein BM‐40 (SPARC, osteonectin)
Authors:
- 29 August 1988
- journal article
- Published by Wiley in FEBS Letters
- Vol. 236 (2) , 352-356
Abstract
Amino acid sequences of 285 and 286 residues, respectively, were deduced for mouse and human BM‐40 from cDNA clones isolated from expression libraries. The sequences showed 92% identity and were also essentially identical to those of bone osteonectin and of the parietal endoderm protein SPARC. About 60% of the mouse BM‐40 sequence was confirmed by Edman degradation. Two of the seven disulfide bonds were localized which apparently separate two distinct domains of mouse BM‐40.Keywords
This publication has 17 references indexed in Scilit:
- Isolation of the osteonectin gene: evidence that a variable region of the osteonectin molecule is encoded within one exonBiochemistry, 1988
- Laminin and Other Basement Membrane ComponentsAnnual Review of Cell Biology, 1987
- Calcium binding domains and calcium-induced conformational transition of SPARC/BM-40/osteonectin, an extracellular glycoprotein expressed in mineralized and nonmineralized tissuesBiochemistry, 1987
- Characterization of three constituent chains of collagen type VI by peptide sequences and cDNA clonesEuropean Journal of Biochemistry, 1987
- In vivo expression of mRNA for the Ca++-binding protein SPARC (osteonectin) revealed by in situ hybridization.Journal of Cell Biology, 1987
- Solubilization of protein BM‐40 from a basement membrane tumor with cheating agents and evidence for its identity with osteonectin and SPARCFEBS Letters, 1987
- Purification and tissue distribution of a small protein (BM-40) extracted from a basement membrane tumorEuropean Journal of Biochemistry, 1986
- Normal and abnormal aspects of proteinuriaExperimental pathology, 1986
- Supercoil Sequencing: A Fast and Simple Method for Sequencing Plasmid DNADNA, 1985
- Osteonectin, a bone-specific protein linking mineral to collagenCell, 1981