Synthesis of novel oxadiazole derivatives: DFT calculations, molecular docking studies, and in vitro, in vivo evaluation of antidiabetic activity using Drosophila melanogaster model
Authors:
- Govinda AnjanayyaGAGovinda Anjanayya
- Ramesh GaniRGRamesh Gani
- Avinash KudvaAKAvinash Kudva
- Shrinivas JoshiSJShrinivas Joshi
- Murigendra HiremathMHMurigendra Hiremath
- Apsara KavitalAKApsara Kavital
- Karabasanagouda TimanagoudaKTKarabasanagouda Timanagouda
- Basavarajaiah MathadaBMBasavarajaiah Mathada
- Mohammad JaveedMJMohammad Javeed
- Raifa AzizRARaifa Aziz
- Shamprasad RaghuSRShamprasad Raghu
- 26 July 2024
- journal article
- research article
- Published by Springer Nature in Journal of the Iranian Chemical Society
- Vol. 21 (8) , 2221-2237
Abstract
No abstract availableKeywords
This publication has 59 references indexed in Scilit:
- New benzimidazole‐oxadiazole derivatives: Synthesis, α‐glucosidase, α‐amylase activity, and molecular modeling studies as potential antidiabetic agentsArchiv der Pharmazie, 2023
- Dextran sodium sulfate alters antioxidant status in the gut affecting the survival of Drosophila melanogaster3 Biotech, 2022
- Synthesis, spectral analysis, DFT calculations, biological potential and molecular docking studies of indole appended pyrazolo-triazineMolecular Diversity, 2022
- Design, synthesis, in vitro evaluation, and docking studies on ibuprofen derived 1,3,4-oxadiazole derivatives as dual α-glucosidase and urease inhibitorsMedicinal Chemistry Research, 2022
- Purple onion in combination with garlic exerts better ameliorative effects on selected biomarkers in high-sucrose diet-fed fruit fly (Drosophila melanogaster)Comparative Clinical Pathology, 2020
- Oxindole based oxadiazole hybrid analogs: Novel α -glucosidase inhibitorsBioorganic Chemistry, 2018
- Synthesis and in silico studies of novel sulfonamides having oxadiazole ring: As β -glucuronidase inhibitorsBioorganic Chemistry, 2017
- α‐Amylase inhibitors from an Indonesian medicinal herb, Phyllanthus urinariaJournal of the Science of Food and Agriculture, 2011
- Management of hyperglycaemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapyDiabetologia, 2006
- Further kinetic and structural characterization of the lysosomal α-d-glucoside glucohydrolase from cattle liverBiochimica et Biophysica Acta (BBA) - Enzymology, 1970