Bacterial antigens in synovial biopsy specimens in yersinia triggered reactive arthritis.
Authors:
- K.O SöderströmKSK.O Söderström
- R Lahesmaa-RantalaRLR Lahesmaa-Rantala
- K GranforsKGK Granfors
- A ToivanenATA Toivanen
Open Access
- 1 February 1991
- journal article
- Published by Elsevier in Annals of the Rheumatic Diseases
- Vol. 50 (2) , 87-90
Abstract
Non-viable structures of Yersinia enterocolitica O:3 were shown at the site of inflammation within mononuclear cells in the synovial membrane of eight out of 10 patients with yersinia triggered reactive arthritis. An avidin-biotin-peroxidase complex method, with a rabbit antiserum specific for Y enterocolitica O:3, was used to visualise yersinia structures. All 13 control samples were negative except for one with non-specific mast cell staining. The findings emphasise the significance of foreign material in the initiation of synovitis in reactive arthritis.Keywords
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