Exercise During Chemotherapy for Cancer: A Systematic Review
Authors:
Open Access
- 23 October 2024
- journal article
- research article
- Published by Wiley in Journal of Surgical Oncology
- Vol. 130 (8) , 1725-1736
Abstract
Exercise prehabilitation may improve the tolerance and effectiveness of anticancer treatments such as chemotherapy. This systematic review assesses the impact of exercise on chemotherapy outcomes and identifies research priorities. Nineteen studies (1418 patients) were reviewed, including 11 randomised controlled trials and eight observational studies. Exercise led to improvements in body composition, fitness, strength and quality of life (QoL) across studies. Exercise can be safely and effectively delivered during chemotherapy. Limited standardisation and small sample sizes highlight the need for larger, better‐designed studies to optimise this low‐cost intervention.Keywords
This publication has 33 references indexed in Scilit:
- Effects of exercise during and after neoadjuvant chemoradiation on symptom burden and quality of life in rectal cancer patients: a phase II randomized controlled trialJournal of Cancer Survivorship, 2021
- Cardiopulmonary exercise testing has greater prognostic value than sarcopenia in oesophago‐gastric cancer patients undergoing neoadjuvant therapy and surgical resectionJournal of Surgical Oncology, 2021
- Effect of high-intensity interval training on patient-reported outcomes and physical function in women with breast cancer receiving anthracycline-based chemotherapySupportive Care in Cancer, 2021
- Effects of exercise on inflammation in patients receiving chemotherapy: a nationwide NCORP randomized clinical trialSupportive Care in Cancer, 2019
- Safety and feasibility of preoperative exercise training during neoadjuvant treatment before surgery for adenocarcinoma of the gastro-oesophageal junctionBJS Open, 2018
- Exercise improves functional capacity and lean body mass in patients with gastrointestinal cancer during chemotherapy: a single-blind RCTSupportive Care in Cancer, 2018
- Cardiopulmonary fitness before and after neoadjuvant chemotherapy in patients with oesophagogastric cancerBritish Journal of Surgery, 2018
- Highly favorable physiological responses to concurrent resistance and high-intensity interval training during chemotherapy: the OptiTrain breast cancer trialBreast Cancer Research and Treatment, 2018
- Low skeletal muscle radiation attenuation and visceral adiposity are associated with overall survival and surgical site infections in patients with pancreatic cancerJournal of Cachexia, Sarcopenia and Muscle, 2016
- Benefits of 24 versus 12 weeks of exercise and wellness programming for women undergoing treatment for breast cancerSupportive Care in Cancer, 2016