Imtiaz Wani has a total of 580 co-authors. Here are the top co-authors by number of shared publications:


Latest Publications

  • Open Access

    Procalcitonin-Informed Decision-Making in Abdominal and Emergency Surgery: A WSES Position Paper

    by Fausto Catena, Belinda De Simone, Igor A. Kryvoruchko, Salomone Di Saverio, Marcelo A. F. Ribeiro, Timothy Craig Hardcastle, Arda Işık, Orestis Ioannidis, Mauro Podda, Marcello Di Martino, et al.

    Background: Procalcitonin (PCT) may support decision-making in abdominal and emergency surgery when infection is difficult to distinguish from non-infectious inflammation. Its interpretation remains challenging because clinical settings, sampling schedules, and proposed thresholds vary. This WSES position paper examines the evidence across six clinical scenarios to provide a practical framework for PCT-informed decision-making. Methods: A structured literature review covering January 1980 to December 2025, with targeted updates through August 2026, informed six PICO-based clinical questions. Evidence appraisal drew on selected GRADE domains, including consistency, directness, and precision. Recommendations were developed through iterative expert review and consensus. Results: The panel formulated six conditional recommendations addressing intra-abdominal infection diagnosis, antibiotic discontinuation after source control, suspected source-control failure, infected pancreatic necrosis, infectious complications after trauma, and postoperative anastomotic leak. The panel’s qualitative assessment rated evidence certainty as moderate for antibiotic discontinuation and the pancreatitis domain, and low for the remaining domains. Serial PCT trends may complement clinical assessment in selected patients. Evidence for reduced antibiotic exposure with predefined PCT algorithms is more established than evidence that PCT-informed imaging, reintervention, or discharge decisions improve patient outcomes. Conclusions: PCT-informed decision-making in abdominal surgery may contribute to a more individualized approach to emergency surgical care and precision emergency surgery. When interpreted as part of serial assessment and integrated with clinical judgement, organ-dysfunction trends, microbiology, imaging, and evaluation of source-control adequacy, PCT may support individualized antibiotic discontinuation, potentially earlier recognition of an unfavourable clinical course, and more timely diagnostic and source-control reassessment. Current evidence does not support universal thresholds or routine serial testing in all surgical patients. Biomarker kinetics should strengthen, but not replace, surgical reasoning or independently determine antimicrobial, imaging, or interventional decisions. Future research should validate setting-specific thresholds and sampling schedules, establish whether PCT provides actionable information before clinical deterioration, and evaluate the clinical effects and cost-effectiveness of PCT-informed pathways.

  • Open Access

    Subareolar breast abscess in males

    by Imtiaz Wani, Gulam Naikoo, Rauf A Wani, Munir A Wani

    BACKGROUND Subareolar breast abscess is extremely rare in males. Only a few cases of male breast abscess are reported in the literature till date. The clinical presentation of male breast include pain, periareolar swelling, tenderness and abscess formation. AIM To study occurrence of subareolar breast abscess in males. METHODS A retrospective study of 11 males from April 2014 to July 2024 is reported who presented with subareolar breast abscess. RESULTS Nine cases had uncomplicated and idiopathic abscess, and one has diabetes and another has underlying carcinoma breast. Incision drainage was done in 7 cases and one who has underlying carcinoma was managed by local toilet and antibiotics whereas rest two had needle aspiration for pus and other two had conservative treatment by antibiotics only. Pus culture predominantly yielded growth of Staphylococus . CONCLUSION Subareolar breast abscess is rare in males. Incision and drainage is treatment of choice in an uncomplicated cases.

  • Open Access

    Laparoscopic Cholecystectomy in Moynihan's Hump, Varices of Paracholedochal Plexuses With Superficial Course of Inferior Vena Cava at Calot's Triangle: Case Report

    by Imtiaz Wani

    Anatomical variations of the vascular supply of the hepatobiliary system are rare to see. A sound knowledge of congenital variations of vascular patterns in and around Calot's triangle is essential for the safe practice of laparoscopic cholecystectomy. A case of 34‐year‐old female is reported who has intraoperative diagnosis of Moynihan's hump, varices of paracholedochal plexuses, superficially placed portal vein in anterior plane with superficial course of inferior vena cava at Calot's triangle during laparoscopic cholecystectomy. An uneventful laparoscopic cholecystectomy was done with utmost meticulous approach and careful surgical dissection in Calot's triangle to avoid any inadvertent injury to anomalous vasculature. An occurrence of congenital anomaly of Moynihan's hump, varices of paracholedochal plexuses, superficially placed portal vein in anterior plane with superficial course of inferior vena cava at Calot's triangle is extremely rare and incidentally diagnosed intraoperatively. This case report is the first kind of case of world reporting occurrence of a multiple vascular anomalies diagnosed during laparoscopic cholecystectomy. Culture of safe practice of laparoscopic cholecystectomy is to be advocated and this is to be called as “Srinagar Cholecystectomy”.

  • Open Access

    Two indirect sacs and one canal of Nuck in female inguinal hernia: a case report

    by Imtiaz Wani

    Female inguinal hernias are rare to see. All inguinal hernias in females occur as indirect hernias. A single hernia sac is usually seen, but the occurrence of more than one sac in female indirect inguinal hernias is extremely rare. A 64-year-old female of Kashmiri ethnicity who had multiple comorbidities reported with right groin swelling. She had a diagnosis of a right indirect inguinal hernia. Intraoperatively, one canal of Nuck and two sacs of an indirect type were diagnosed. Occurrence of two hernia sacs of an indirect type and canal of Nuck in female inguinal hernia is an extremely rare occurrence. This is the first case report in the world of a female indirect inguinal hernia being reported having two individual hernia sacs and a single canal of Nuck present. This hernia is named “the Srinagar” hernia after its region of origin.


  • Top Cited Papers
    Open Access

    Source control in emergency general surgery: WSES, GAIS, SIS-E, SIS-A guidelines

    by Federico Coccolini, Massimo Sartelli, Robert Sawyer, Kemal Rasa, Bruno Viaggi, Fikri Abu-Zidan, Kjetil Soreide, Timothy Hardcastle, Deepak Gupta, Cino Bendinelli, et al.

    Intra-abdominal infections (IAI) are among the most common global healthcare challenges and they are usually precipitated by disruption to the gastrointestinal (GI) tract. Their successful management typically requires intensive resource utilization, and despite the best therapies, morbidity and mortality remain high. One of the main issues required to appropriately treat IAI that differs from the other etiologies of sepsis is the frequent requirement to provide physical source control. Fortunately, dramatic advances have been made in this aspect of treatment. Historically, source control was left to surgeons only. With new technologies non-surgical less invasive interventional procedures have been introduced. Alternatively, in addition to formal surgery open abdomen techniques have long been proposed as aiding source control in severe intra-abdominal sepsis. It is ironic that while a lack or even delay regarding source control clearly associates with death, it is a concept that remains poorly described. For example, no conclusive definition of source control technique or even adequacy has been universally accepted. Practically, source control involves a complex definition encompassing several factors including the causative event, source of infection bacteria, local bacterial flora, patient condition, and his/her eventual comorbidities. With greater understanding of the systemic pathobiology of sepsis and the profound implications of the human microbiome, adequate source control is no longer only a surgical issue but one that requires a multidisciplinary, multimodality approach. Thus, while any breach in the GI tract must be controlled, source control should also attempt to control the generation and propagation of the systemic biomediators and dysbiotic influences on the microbiome that perpetuate multi-system organ failure and death. Given these increased complexities, the present paper represents the current opinions and recommendations for future research of the World Society of Emergency Surgery, of the Global Alliance for Infections in Surgery of Surgical Infection Society Europe and Surgical Infection Society America regarding the concepts and operational adequacy of source control in intra-abdominal infections.


  • Open Access

    Postoperative pain management in non-traumatic emergency general surgery: WSES-GAIS-SIAARTI-AAST guidelines

    by Federico Coccolini, Francesco Corradi, Massimo Sartelli, Raul Coimbra, Igor A. Kryvoruchko, Ari Leppaniemi, Krstina Doklestic, Elena Bignami, Giandomenico Biancofiore, Miklosh Bala, et al.

    Background: Non-traumatic emergency general surgery involves a heterogeneous population that may present with several underlying diseases. Timeous emergency surgical treatment should be supplemented with high-quality perioperative care, ideally performed by multidisciplinary teams trained to identify and handle complex postoperative courses. Uncontrolled or poorly controlled acute postoperative pain may result in significant complications. While pain management after elective surgery has been standardized in perioperative pathways, the traditional perioperative treatment of patients undergoing emergency surgery is often a haphazard practice. The present recommended pain management guidelines are for pain management after non-traumatic emergency surgical intervention. It is meant to provide clinicians a list of indications to prescribe the optimal analgesics even in the absence of a multidisciplinary pain team. Material and methods: An international expert panel discussed the different issues in subsequent rounds. Four international recognized scientific societies: World Society of Emergency Surgery (WSES), Global Alliance for Infection in Surgery (GAIS), Italian Society of Anesthesia, Analgesia Intensive Care (SIAARTI), and American Association for the Surgery of Trauma (AAST), endorsed the project and approved the final manuscript. Conclusion: Dealing with acute postoperative pain in the emergency abdominal surgery setting is complex, requires special attention, and should be multidisciplinary. Several tools are available, and their combination is mandatory whenever is possible. Analgesic approach to the various situations and conditions should be patient based and tailored according to procedure, pathology, age, response, and available expertise. A better understanding of the patho-mechanisms of postoperative pain for short- and long-term outcomes is necessary to improve prophylactic and treatment strategies.


  • Open Access

    The LIFE TRIAD of emergency general surgery

    by Federico Coccolini, Massimo Sartelli, Yoram Kluger, Aleksei Osipov, Yunfeng Cui, Solomon Gurmu Beka, Andrew Kirkpatrick, Ibrahima Sall, Ernest E. Moore, Walter L. Biffl, et al.

    Emergency General Surgery (EGS) was identified as multidisciplinary surgery performed for traumatic and non-traumatic acute conditions during the same admission in the hospital by general emergency surgeons and other specialists. It is the most diffused surgical discipline in the world. To live and grow strong EGS necessitates three fundamental parts: emergency and elective continuous surgical practice, evidence generation through clinical registries and data accrual, and indications and guidelines production: the LIFE TRIAD.


  • Open Access

    It’s time for a minimum synoptic operation template in patients undergoing laparoscopic cholecystectomy: a systematic review

    by Niall O’cOnnor, Michael Sugrue, Conor Melly, Gearoid McGeehan, Magda Bucholc, Aileen Crawford, Paul O’cOnnor, Fikri Abu-Zidan, Imtiaz Wani, Zsolt J. Balogh, et al.

    Background: Despite the call to enhance accuracy and value of operation records few international recommended minimal standards for operative notes documentation have been described. This study undertook a systematic review of existing operative reporting systems for laparoscopic cholecystectomy (LC) to fashion a comprehensive, synoptic operative reporting template for the future. Methods: A search for all relevant articles was conducted using PubMed version of Medline, Scopus and Web of Science databases in June 2021, for publications from January 1st 2011 to October 25th 2021, using the keywords: laparoscopic cholecystectomy AND operation notes OR operative notes OR proforma OR documentation OR report OR narrative OR audio-visual OR synoptic OR digital. Two reviewers (NOC, GMC) independently assessed each published study using a MINORS score of ≥ 16 for comparative and ≥ 10 for non-comparative for inclusion. This systematic review followed PRISMA guidelines and was registered with PROSPERO. Synoptic operative templates from published data were assimilated into one “ideal” laparoscopic operative report template following international input from the World Society of Emergency Surgery board. Results: A total of 3567 articles were reviewed. Following MINORS grading 25 studies were selected spanning 14 countries and 4 continents. Twenty-two studies were prospective. A holistic overview of the operative procedure documentation was reported in 6/25 studies and a further 19 papers dealt with selective surgical aspects of LC. A unique synoptic LC operative reporting template was developed and translated into Chinese/Mandarin, French and Arabic. Conclusion: This systematic review identified a paucity of publications dealing with operative reporting of LC. The proposed new template may be integrated digitally with hospitals’ medical systems and include additional narrative text and audio-visual data. The template may help define new OR (operating room) recording standards and impact on care for patients undergoing LC.


  • Top Cited Papers
    Open Access

    Acute abdomen in the immunocompromised patient: WSES, SIS-E, WSIS, AAST, and GAIS guidelines

    by Federico Coccolini, Mario Improta, Massimo Sartelli, Kemal Rasa, Robert Sawyer, Raul Coimbra, Massimo Chiarugi, Andrey Litvin, Timothy Hardcastle, Francesco Forfori, et al.

    Immunocompromised patients are a heterogeneous and diffuse category frequently presenting to the emergency department with acute surgical diseases. Diagnosis and treatment in immunocompromised patients are often complex and must be multidisciplinary. Misdiagnosis of an acute surgical disease may be followed by increased morbidity and mortality. Delayed diagnosis and treatment of surgical disease occur; these patients may seek medical assistance late because their symptoms are often ambiguous. Also, they develop unique surgical problems that do not affect the general population. Management of this population must be multidisciplinary.This paper presents the World Society of Emergency Surgery (WSES), Surgical Infection Society Europe (SIS-E), World Surgical Infection Society (WSIS), American Association for the Surgery of Trauma (AAST), and Global Alliance for Infection in Surgery (GAIS) joined guidelines about the management of acute abdomen in immunocompromised patients.


  • Top Cited Papers
    Open Access

    2020 World Society of Emergency Surgery updated guidelines for the diagnosis and treatment of acute calculus cholecystitis

    by Michele Pisano, Niccolò Allievi, Kurinchi Gurusamy, Giuseppe Borzellino, Stefania Cimbanassi, Djamila Boerna, Federico Coccolini, Andrea Tufo, Marcello Di Martino, Jeffrey Leung, et al.

    Background: Acute calculus cholecystitis (ACC) has a high incidence in the general population. The presence of several areas of uncertainty, along with the availability of new evidence, prompted the current update of the 2016 WSES (World Society of Emergency Surgery) Guidelines on ACC.Materials and methods: The WSES president appointed four members as a scientific secretariat, four members as an organization committee and four members as a scientific committee, choosing them from the expert affiliates of WSES. Relevant key questions were constructed, and the task force produced drafts of each section based on the best scientific evidence from PubMed and EMBASE Library; recommendations were developed in order to answer these key questions. The quality of evidence and strength of recommendations were reviewed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) criteria (seehttps://www.gradeworkinggroup.org/). All the statements were presented, discussed and voted upon during the Consensus Conference at the 6th World Congress of the World Society of Emergency Surgery held in Nijmegen (NL) in May 2019. A revised version of the statements was voted upon via an online questionnaire until consensus was reached.Results: The pivotal role of surgery is confirmed, including in high-risk patients. When compared with the WSES 2016 guidelines, the role of gallbladder drainage is reduced, despite the considerable technical improvements available. Early laparoscopic cholecystectomy (ELC) should be the standard of care whenever possible, even in subgroups of patients who are considered fragile, such as the elderly; those with cardiac disease, renal disease and cirrhosis; or those who are generally at high risk for surgery. Subtotal cholecystectomy is safe and represents a valuable option in cases of difficult gallbladder removal.Conclusions, knowledge gaps and research recommendations: ELC has a central role in the management of patients with ACC. The value of surgical treatment for high-risk patients should lead to a distinction between high-risk patients and patients who are not suitable for surgery. Further evidence on the role of clinical judgement and the use of clinical scores as adjunctive tools to guide treatment of high-risk patients and patients who are not suitable for surgery is required. The development of local policies for safe laparoscopic cholecystectomy is recommended.