Muhammet Fatih Topuz

Objectives: In this study, the objective was to compare the effectiveness of fluticasone dipropionate and platelet-rich plasma treatments added to the treatment in patients undergoing functional endoscopic sinus surgery in patients with chronic sinusitis involving odor dysfunction, different stages and types of sinusitis. Methods: The study included a total of 60 patients between 18 and 60 years who underwent endoscopic sinus surgery due to chronic paranasal sinus infection followed by olfactory dysfunction. Group 1: paranasal sinus surgery + steroid therapy (first 30 patients) and Group 2: paranasal sinus surgery + steroid therapy + PRP therapy (second 30 patients) were grouped together without the patients' knowledge of the operating physician and of the treatment protocol. For the paranasal sinus CT evaluation, Lund-Mackey staging was used and the degree of the disease was determined using the Kennedy staging system. Modified Sniffin Stick test was applied to all patients in the preoperative 1st week and in the 3rd month postoperatively. The Modified Sniffin Stick test was conducted on all patients during the preoperative 1st week and the postoperative 3rd month. The modified Sniffin Stick test and endoscopic evaluation score were evaluated and whether or not the patients benefited from PRP treatment were compared. Results: According to the postoperative endoscopy score, there was a difference between the experimental group and the control group in terms of postoperative endoscopy score, and it was found to be statistically significant. Besides, the postoperative endoscopy score of the experimental group was found to be lower than the control group. The average of Modified Sniffin’ Stick Test scores in the postoperative period of the patients in the study was 28.27 ± 7.88 for the experimental group, while it was determined as 20.08 ± 5.75 for the control group, and this difference was statistically significant. The average anosmia times of the experimental and control group patients in the study were compared, and the mean duration of anosmia was 48.53 ± 20.40 (6-96) for the experimental group and 44.27 ± 19.45 (6.96) for the control group. The difference in the mean duration of anosmia between the experimental and control groups was not found statistically significant. Conclusions: In this research, PRP, which is applied to functional endoscopic sinus surgery and fluticasone dipropionate treatment, has been shown to be a readily applicable, safe and highly efficient method of treatment in patients with chronic sinusitis accompanied by smell dysfunction.

Günümüz modern eğitim sistemleri sınavlara salt bilgi yerine kazanılmış beceri yada öğrenilmiş bilginin kullanılabilirliğini ölçme görevi yüklemiştir. Sonuçta bireylere sorunları analiz edip çözüm üretebilme yeteneği kazandırmak nihayi hedeftir. Bu kitabın temelinde bu bakış akıcısı gözönünde tutulmuş olup verilen gerçek vaka örneklerinde dikkatle sorgulanması gereken detaylara, atlanmaması gereken fizik muayene yöntemlerine, öncelikli seçilmesi gereken tanı testlerine, ayırıcı tanıda gözönünüde bulundurulması gereken hastalıklara, kesin tanı yöntemlerine, hazırlıklı olunması gereken komplikasyonlara ve hasta takibindeki önemli unsurlara çözümsel yaklaşım aktarılmaya çalışılmıştır.

Şahinde Atlanoğlu, Muhammed Fatih Topuz. JKAOMS 2022;48:149-54. https://doi.org/10.5125/jkaoms.2022.48.3.149

Amaç: 1892-2021 yılları arasında Türkiye’de otoloji- nörotoloji alanında yayınlanan kitapların niceliksel analizinin yapıldığı bibliyometrik araştırma amaçlanmıştır.Yöntemler: Otoloji-nörotoloji alanında 1892-2021 yıllar arasında yayınlanan kitapların saptanmasında Milli kütüphane kâşif otomasyon sistemi, Türkiye’de kitap satışı yapan elektronik sahaf ve yayınevlerinin resmi internet sayfasında bulunan veri tabanı ve Türk kulak burun boğaz bibliyografyası kitabı kullanılmıştır. Tespit edilen kitapların yazar, yayınlandığı yıl, yayınlandığı şehir, konu değerlendirmesi, tercüme ve telif eser, basım sayısı özellikleri değerlendirilmiştir. Bulgular: 1892 yılından 21 Ağustos 2021 tarihine kadar ülkemizde yayınlanmış otoloji-nörotoloji kitap sayısı 41 olarak tespit edilmiştir. İlk otoloji kitabının 1892 yılında Mehmet Neşet tarafından İstanbul’da yayınlandığı tespit edilmiştir. Araştırmamızdaki en güncel kitabın ise Fuat Bulut tarafından 2021 yılında Ankara’da yayınlandığı saptanmıştır. Çalışmaya dahil edilen 41 kitabın sadece 7 tanesi tercüme eser özelliğinde, 34 kitabın ise telif eser niteliğinde olduğu saptanmıştır. Basım özellikleri açısından 7 kitabın ikinci basım yapıldığı, diğer 34 kitabın ise sadece bir kez basım yapıldığı saptanmıştır. Kitapların zaman dilimlerine göre sınıflandırılmasında en az kitabın yayınlandığı tarihin 1911-1930 yılları arası, en çok kitabın yayınlandığı tarihin ise 2011-2021 yılları arasında olduğu tespit edilmiştir. Kitapların basıldığı şehirler açısından incelenmesinde 24 kitapla en fazla kitabın İstanbul’da, 13 kitabın ise Ankara’da yayınlandığı saptanmıştır. Kitapların alt konuya göre incelenmesinde genel otoloji alanında 12, odyoloji hakkında 11, otolojik cerrahi hakkında 8 kitap yayınlandığı tespit edilmiştir.Sonuç: Türkiye’de otoloji-nörotoloji alanında yayınlanan kitap sayısındaki artış ve kitapların konu çeşitliliği heyecan vericidir. Bundan sonraki çalışmalarda atıf analizi araştırılmasının yapılması kitapların niteliksel değerlendirilmesini sağlayacaktır.

Duyu organları ile yakın ilişkisi olan kulak, burun, boğaz ve baş boyun cerrahisi tıbbın branşlaşmaya başladığı ilk dönemlerde ortaya çıkmış olup klinik pratikte kapsamı genişleyerek zenginleşen bir branş olarak önemini korumaktadır. Günümüzde otoloji, rinoloji, laringoloji, fasiyal plastik ve rekonstruktif cerrahi, baş boyun cerrahisi, pediatrik kulak burun boğaz ve uyku tıbbı başlıkları bu branşın konuları arasında bulunur. İçeriğindeki genişliğin artması yazılı kaynakların pratik kullanıma uygun yazılmasının önemini ortaya çıkarmaktadır. Bu amaçla yazarları uzman hekimlerden oluşturulan ve okuyucularının da uzman hekim olması hedeflenen kitabımızda bilim dili olarak Türkçenin yalın olarak kullanılması, güncel kaynakların ele alınması konu için dönüm noktası olan yayınların ve analizlerin atlanmamasına özen gösterilmesi ve kullanımının kolay olması editörler ve yazarlarımızın amacı olmuştur.

Objective This study aims to explore the importance of systemic immune-inflammation index (SII) in patients diagnosed with obstructive sleep apnea (OSA). Materials and method In this study planned as a retrospective cohort, the files of the patients who presented with sleep apnea/snoring complaint between 10.01.2017 and 10.01.2021 and underwent polysomnography (PSG) and complete blood count analyses were reviewed. PSG findings (age, sex, body mass index (BMI), apnea–hypopnea index (AHI), mean oxygen saturation) were compared with SII in 194 patients meeting study eligibility criteria. Results Patients included in this study were divided into 4 groups by AHI value. Statistical difference was detected between the groups in terms of age, sex, body mass index (BMI), and mean oxygen saturation (p < 0.05). There is an approximately 30% positive statistically significant correlation between the severity of OSA and SII (p < 0.001). As for the mean SII values of the AHI groups, it was observed that the more severe AHI is, the higher the mean SII value is. The correlation between SII and the severity of OSA was found to be more significant than the correlation with neutrophil–lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR). Conclusion There is a significant correlation between SII and the severity of OSA. This correlation is stronger compared to NLR and PLR. SII can be used to demonstrate the chronic systemic inflammation observed in OSA patients, and can be utilized as a simple and inexpensive biomarker as it can be easily calculated from the parameters present in routine blood analyses.

Purpose We aimed to evaluate oxidative stress in patients with peripheral vertigo by measuring serum prolidase, malondialdehyde (MDA) and catalase levels. Methods A total of 30 patients (age: 60 <) with peripheral vertigo and 30 healthy subjects were recruited. Blood samples were collected from both groups and serum prolidase levels were measured using enzyme-linked immunosorbent assay (ELISA). MDA and catalase levels were measured by the spectrophotometric method. Results The most common cause of vertigo was BPPV (53.3%), followed by Ménière’s disease (16.6%), vestibular neuritis (13.3%), lateral semicircular canal fistula (3.3%), and idiopathic vertigo (13.3%). Mean serum prolidase activity and MDA levels were significantly higher in the vertigo patients than in the control subjects (P < 0.05); however, there was no statistically significant difference in mean serum catalase levels between the groups (P > 0.05). Conclusion We concluded that serum prolidase and MDA levels may be used as markers of oxidative stress in patients with peripheral vertigo.

To evaluate the validity and reliability of the Fonseca anamnestic index (FAI) over time in Turkish females. Four hundred-fourteen patients who visited the otorhinolaryngology clinic were initially...

Objective: The objective of this study was to review the articles on otology-neurotology submitted from Turkey and published in Science Citation Indexed (SCI) and Science Citation Index-Expanded (SCI-E) journals in the period from 2012 through 2016 in terms of characteristics and quantity, and to analyze the variances in these parameters over the defined time period to profile the national scientific endeavor in the field. Methods: We searched the papers on otology-neurotology and related subjects that were submitted from Turkey and published in the period from 2012 through 2016 in the relevant journals listed in SCI and SCI-E. We noted the impact factors and quartile rankings of the publishing journals, and reviewed, counted and classified the titles, subjects, types and characteristics of the articles that met our criteria. Results: A total of 546 papers from Turkey were published in 25 SCI and SCI-E listed journals (145 and 401, respectively) in the defined period. The impact factors of these 25 journals ranged from 0.392 to 2.951. Of these papers, 393 (71.97%) were experimental or observational clinical studies, case reports, or surveys; 137 (25.10%) were non-clinical, laboratory or animal experiments; and the remaining 16 (2.93%) were reviews or letters to the editor. Conclusion: A substantial number of papers on otology-neurotology submitted from Turkey were published in many prestigious SCI-journals, however, we did not find any significant increase in this number in the given period. We also found concentration of articles in certain journals and inclination to a few subjects and would like to underline that the number of basic science and ecological-epidemiological studies within the confines of our review were relatively few.