Ying Huang
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Ying Huang has a total of 11 co-authors. Here are the top co-authors by number of shared publications:
- Bing Lang
Key Laboratory of Arrhythmias, Ministry of Education of China, East Hospital, Shanghai, 200092, People's Republic of China
1 shared publication - Can-Can Shao
Department of Histology and Embryology, Institute of Neuroscience, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, People's Republic of China
1 shared publication - Chan Zhang
Department of Histology and Embryology, Institute of Neuroscience, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, People's Republic of China
1 shared publication - Cong-Cong Qi
Department of Laboratory Animal Science, Fudan University, Shanghai 200000, China
1 shared publication - Jin-Bao Zhang
Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University
1 shared publication - Ling Chen
Key Laboratory of Arrhythmias, Ministry of Education of China, East Hospital, Shanghai, 200092, People's Republic of China
1 shared publication
Latest Publications
- Open Access
- 13 December 2016
- Published by Springer Nature in Molecular Brain
- Vol. 9 (1) , 1-13
Oxytocin is implicated in social memory deficits induced by early sensory deprivation in mice
Early-life sensory input plays a crucial role in brain development. Although deprivation of orofacial sensory input at perinatal stages disrupts the establishment of the barrel cortex and relevant callosal connections, its long-term effect on adult behavior remains elusive. In this study, we investigated the behavioral phenotypes in adult mice with unilateral transection of the infraorbital nerve (ION) at postnatal day 3 (P3). Although ION-transected mice had normal locomotor activity, motor coordination, olfaction, anxiety-like behaviors, novel object memory, preference for social novelty and sociability, they presented deficits in social memory and spatial memory compared with control mice. In addition, the social memory deficit was associated with reduced oxytocin (OXT) levels in the hypothalamus and could be partially restored by intranasal administration of OXT. Thus, early sensory deprivation does result in behavioral alterations in mice, some of which may be associated with the disruption of oxytocin signaling.
- 13 December 2016
- Published by Springer Nature in Molecular Brain
- Vol. 9 (1) , 1-13
Open AccessOxytocin is implicated in social memory deficits induced by early sensory deprivation in mice
Early-life sensory input plays a crucial role in brain development. Although deprivation of orofacial sensory input at perinatal stages disrupts the establishment of the barrel cortex and relevant callosal connections, its long-term effect on adult behavior remains elusive. In this study, we investigated the behavioral phenotypes in adult mice with unilateral transection of the infraorbital nerve (ION) at postnatal day 3 (P3). Although ION-transected mice had normal locomotor activity, motor coordination, olfaction, anxiety-like behaviors, novel object memory, preference for social novelty and sociability, they presented deficits in social memory and spatial memory compared with control mice. In addition, the social memory deficit was associated with reduced oxytocin (OXT) levels in the hypothalamus and could be partially restored by intranasal administration of OXT. Thus, early sensory deprivation does result in behavioral alterations in mice, some of which may be associated with the disruption of oxytocin signaling.