Renjie Li
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Renjie Li has a total of 11 co-authors. Here are the top co-authors by number of shared publications:
- Zhenbo Tong
School of Energy and Environment, Southeast University, Nanjing, China
2 shared publications - Aibing Yu
Center for Energy and Environment, Southeast University-Monash University Joint Research Institute, Suzhou, P.R. China
1 shared publication - Fen Huang
Key Laboratory of Energy Thermal Conversion and Control of Ministry of Education, Southeast University, Nanjing 210096, China
1 shared publication - Hao Miao
Department of Chemical and Biological Engineering, Monash University, Clayton, VIC 3800, Australia; Monash Suzhou Research Institute, Suzhou 215000, China
1 shared publication - Jiaqi Yu
Jiangsu Industrial Technology ResearchInstitute for Process and Optimization, Suzhou 215123, China
1 shared publication Jingyu Shi
School of Energy and Environment, Southeast University, Nanjing 210000, China; Southeast University-Monash University Joint Research Institute, Suzhou 215000 China
1 shared publication
Latest Publications
- 16 May 2023
- Published by Elsevier in International Journal of Pharmaceutics
- Vol. 640, 123050
Optimization of formulation and atomization of lipid nanoparticles for the inhalation of mRNA
- 16 May 2023
- Published by Elsevier in International Journal of Pharmaceutics
- Vol. 640, 123050
Optimization of formulation and atomization of lipid nanoparticles for the inhalation of mRNA
- Open Access
Numerical and Experimental Investigation on Key Parameters of the Respimat® Spray Inhaler
Respimat®Soft MistTM is a newly developed spray inhaler. Different from traditional nebulizers, metered-dose inhalers, and dry powder inhalers, this new type of inhaler can produce aerosols with long duration, relatively slow speed, and a high content of fine particles. Investigating the effect of the key geometric parameters of the device on the atomization is of great significance for generic product development and inhaler optimization. In this paper, a laser high-speed camera experimental platform is built, and important parameters such as the geometric pattern and particle size distribution of the Respimat®Soft MistTM are measured. Computational fluid dynamics (CFD) and the volume of fluid method coupled with the Shear Stress Transport (SST) k-ω turbulence model are applied to simulate the key geometric parameters of the device. The effects of geometric parameters on the spray velocity distribution and geometric pattern are obtained. The angle of flow collision, the sphere size of the central divider and the length and width of the flow channel show significant impacts on the spray atomization.
Open AccessNumerical and Experimental Investigation on Key Parameters of the Respimat® Spray Inhaler
Respimat®Soft MistTM is a newly developed spray inhaler. Different from traditional nebulizers, metered-dose inhalers, and dry powder inhalers, this new type of inhaler can produce aerosols with long duration, relatively slow speed, and a high content of fine particles. Investigating the effect of the key geometric parameters of the device on the atomization is of great significance for generic product development and inhaler optimization. In this paper, a laser high-speed camera experimental platform is built, and important parameters such as the geometric pattern and particle size distribution of the Respimat®Soft MistTM are measured. Computational fluid dynamics (CFD) and the volume of fluid method coupled with the Shear Stress Transport (SST) k-ω turbulence model are applied to simulate the key geometric parameters of the device. The effects of geometric parameters on the spray velocity distribution and geometric pattern are obtained. The angle of flow collision, the sphere size of the central divider and the length and width of the flow channel show significant impacts on the spray atomization.