Ahmed Hussain Jawhari

The present study illustrated the construction, characterization, and application of a novel tungsten oxide nanoparticle (WO2NPs) based sensors for sensiti

This study presents the green synthesis of CoFe ₂ O ₄ and CoFe ₂ O ₄ -Ag using Pterocarpus marsupium bark extract and their biological and computational validation.

This work describes the fabrication of a reduced graphene oxide-modified screen-printed electrode (rGO-SPE) and its application as a low-cost electrochemical sensor for the determination of Darunavir concentration. This sensor can be fabricated using a screen-printing method and optimized droplet casting, and its modified surface can be characterized using Scanning Electron Microscopy, FTIR, Raman, and EIS techniques. Electrochemical analysis showed that DRV undergoes a two-electron irreversible oxidation under diffusion-controlled conditions, with a peak at pH 8.0. Under optimal conditions for differential pulls, a rGO-SPE with a broad linear dynamic range (41–1351 ng ml ⁻¹ ) and a very low limit of detection (12 ng ml ⁻¹ ) was developed. Additionally, rGO-SPE has demonstrated high precision (RSD ≤ 1.55%) and strong selectivity towards commonly encountered biological and pharmaceutical interferents. Efficiently used with pharmaceuticals and biological fluids, this rGO-SPE has emerged as a highly competent, portable alternative to traditional chromatography-based systems for clinical and pharmaceutical applications and analysis.

A conducting printing carbon ink fortified with iron oxide nanoparticles (FeONPs) was formulated for construction of green screen printed carbon electrodes (FeONPs-gSPCEs). The fabricated electrodes were used for sensitive differential pulse voltammetric quantification of a newly sodium–glucose cotransporter 2–inhibitors canagliflozin (CAN) in its pharmaceutical tablets and biological samples. The ink matrix composition and the FeONPs content were optimized, where the electroanalytical futures and the surface morphology of the printed sensors were deeply characterized. Incorporation of FeONPs improved the sensor performance against the electrooxidation of CAN in BR buffer (pH 7) at 0.952 V following an adsorption-controlled electrode reaction. Comprehensive theoretical molecular orbital calculations suggested the electrooxidation of oxygen atom (O27) within the CAN moiety with the transfer of two electrons and one proton in the electrode reaction. At the optimum analytical conditions, the constructed calibration graphs showed linear dynamic range from 15 to 2348 ng ml ⁻¹ , with LOD value 3.11 ng ml ⁻¹ . The proposed FeONPs based sensors showed high measurement reproducibility, showed prolonged lifetime, and significant selectivity. The greenness of the developed voltammetric sensor was evaluated compared with the reported chromatographic and spectrometric techniques. The tentative oxidation mechanism of CAN was presented in details based on comprehensive DFT computational studies.

A silver–niacin-based MOF was synthesized using a green solvothermal process and thoroughly characterized. The material demonstrated rapid and efficient photocatalytic degradation of malachite green dye with 97% removal in 90 minutes.

Hybrid magnetic nanocomposite, based on Glycyrrhiza glabra (GG), and γ-Fe ₂ O ₃ was synthesized via one-pot co-precipitation method and utilized for adsorption and photocatalytic degradation of Congo red and Nile blue dyes from water.

Antagonistic behavior of leaves extract of Croton bonplandianus towards Meloidogyne incognita: in silico and GC-MS analysis.

Antimicrobial compounds have been gaining paramount importance in recent years since there has been a lot of concern over the increasing threats from microbial infections. Medicinal smoke has always been received with warmth and positivity, and being an age-old traditional process, it has been practiced down the generations. Nanomaterials have become highly promising when it comes to antimicrobial applications, and carbon nanomaterials have also gained preeminence. In the following study, carbon nanodots were extracted and characterized from benzoin resin smoke and tested for their antibacterial, anti-oral bacterial, and anti-biofilm properties. 2–15 nm-sized carbon nanodots were isolated, and their antibacterial activity was validated. Carbon coatings were made on glass using the benzoin resin-extracted carbon nanodots using a simple dip–dry technique. These coatings were confirmed to possess antibiofilm activity against pathogenic Staphylococcus aureus biofilms. With rising concerns over chemically synthesized nanomaterials, green extraction of carbon nanodots from benzoin smoke will come in handy for multiple biomedical applications.

In this study, the establishment and validation of a stable reversed‐phase high‐performance liquid chromatography (RP‐HPLC) method for the concomitant estimation of the two drugs in dosage forms are presented. Method optimization was achieved by response surface methodology (RSM) using Design Expert Software 13, taking into account the special physicochemical characteristics of metoclopramide (MET) (a moderately polar molecule, pKa 9.5) and camylofin (CAM) (a less polar, hydrophobic molecule, pKa 8.7). Chromatographic resolution was achieved on a phenyl‐hexyl column under isocratic mobile phase mode in which methanol and 20 mM ammonium acetate buffer (pH 3.5) were used to provide maximum analyte interaction and resolution. The method was found to have good linearity for both analytes ( R ² > 0.999) over the concentration ranges studied. Limits of detection were 0.23 and 0.15 μg/mL for MET and CAM, respectively, and corresponding limits of quantification were 0.35 and 0.42 μg/mL, respectively. Recovery tests gave high precision values of 98.2%–101.5%, while intra‐ and inter‐day precision in relative standard deviation (RSD) was below 2%. The method was effectively applied for the analysis of commercial tablet formulations, confirming its reliability and suitability for routine quality control and regulatory analyses. Overall, the validated RP‐HPLC method provides a sensitive, accurate, and efficient means of simultaneous determination of MET and CAM in pharmaceutical dosage forms.