M. E. Klepser
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
M. E. Klepser has a total of 2 co-authors. Here are the top co-authors by number of shared publications:
E. J. Wolfe
1 shared publicationM. A. Pfaller
1 shared publication
Latest Publications
- Open Access
- 1 March 1998
- Published by Oxford University Press (OUP) in Journal of Antimicrobial Chemotherapy
- Vol. 41 (3) , 397-401
Antifungal pharmacodynamic characteristics of fluconazole and amphotericin B against Cryptococcus neoformans
The activity of fluconazole and amphotericin B against three isolates of Cryptococcus neoformans was evaluated, with fluconazole and amphotericin B MICs of 2.0-4.0 mg/L and 1.0 mg/L respectively, using time-kill curve methods. Fluconazole was fungistatic against all isolates tested ( or = 99.9% decrease in cfu from initial inoculum). Both the rate and the extent of amphotericin B activity were enhanced when drug concentration was increased.
- 1 March 1998
- Published by Oxford University Press (OUP) in Journal of Antimicrobial Chemotherapy
- Vol. 41 (3) , 397-401
Open AccessAntifungal pharmacodynamic characteristics of fluconazole and amphotericin B against Cryptococcus neoformans
The activity of fluconazole and amphotericin B against three isolates of Cryptococcus neoformans was evaluated, with fluconazole and amphotericin B MICs of 2.0-4.0 mg/L and 1.0 mg/L respectively, using time-kill curve methods. Fluconazole was fungistatic against all isolates tested ( or = 99.9% decrease in cfu from initial inoculum). Both the rate and the extent of amphotericin B activity were enhanced when drug concentration was increased.