Giulia De Marchi
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Giulia De Marchi has a total of 7 co-authors. Here are the top co-authors by number of shared publications:
- Andrew Ofosu
Division of Gastroenterology and Hepatology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
1 shared publication - Federico Caldart
Gastroenterology Unit, Department of Medicine, Pancreas Institute, University of Verona, Piazzale L.A. Scuro 10, 37134 Verona, Italy
1 shared publication - Luca Frulloni
Department of Medicine, Pancreas Institute, University of Verona, Verona, Italy
1 shared publication - Maria Cristina Conti Bellocchi
Diagnostic and Interventional Endoscopy of Pancreas, Pancreas Institute, University of Verona, 37134 Verona, Italy
1 shared publication - Nicolò de Pretis
Gastroenterology Unit, Department of Medicine, University of Verona, Verona, Italy
1 shared publication - Rachele Ciccocioppo
Gastroenterology & Endoscopy Unit, Department of Medicine and Aging Sciences, Ospedale Clinicizzato SS. Annunziata, Gabriele d’Annunzio University, 66100 Chieti, Italy
1 shared publication
Latest Publications
- Open Access
- 8 May 2023
- Published by MDPI AG in Biomedicines
- Vol. 11 (5) , 1393
A Clinical and Pathophysiological Overview of Intestinal and Systemic Diseases Associated with Pancreatic Disorders: Causality or Casualty?
The relationship between chronic intestinal disease, including inflammatory bowel disease (IBD) and celiac disease (CelD), and pancreatic disorders has been little investigated. Although an increased risk of acute pancreatitis (AP), exocrine pancreatic insufficiency with or without chronic pancreatitis, and chronic asymptomatic pancreatic hyperenzymemia have been described in these patients, the pathogenetic link remains unclear. It may potentially involve drugs, altered microcirculation, gut permeability/motility with disruption of enteric-mediated hormone secretion, bacterial translocation, and activation of the gut-associated lymphoid tissue related to chronic inflammation. In addition, the risk of pancreatic cancer seems to be increased in both IBD and CelD patients with unknown pathogenesis. Finally, other systemic conditions (e.g., IgG4-related disease, sarcoidosis, vasculitides) might affect pancreatic gland and the intestinal tract with various clinical manifestations. This review includes the current understandings of this enigmatic association, reporting a clinical and pathophysiological overview about this topic.
- 8 May 2023
- Published by MDPI AG in Biomedicines
- Vol. 11 (5) , 1393
Open AccessA Clinical and Pathophysiological Overview of Intestinal and Systemic Diseases Associated with Pancreatic Disorders: Causality or Casualty?
The relationship between chronic intestinal disease, including inflammatory bowel disease (IBD) and celiac disease (CelD), and pancreatic disorders has been little investigated. Although an increased risk of acute pancreatitis (AP), exocrine pancreatic insufficiency with or without chronic pancreatitis, and chronic asymptomatic pancreatic hyperenzymemia have been described in these patients, the pathogenetic link remains unclear. It may potentially involve drugs, altered microcirculation, gut permeability/motility with disruption of enteric-mediated hormone secretion, bacterial translocation, and activation of the gut-associated lymphoid tissue related to chronic inflammation. In addition, the risk of pancreatic cancer seems to be increased in both IBD and CelD patients with unknown pathogenesis. Finally, other systemic conditions (e.g., IgG4-related disease, sarcoidosis, vasculitides) might affect pancreatic gland and the intestinal tract with various clinical manifestations. This review includes the current understandings of this enigmatic association, reporting a clinical and pathophysiological overview about this topic.