Joanna Stefaniak-Skorupa
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Joanna Stefaniak-Skorupa has a total of 11 co-authors. Here are the top co-authors by number of shared publications:
- Andrzej Stanisław Skwarecki
Department of Pharmaceutical Technology and Biochemistry, Gdańsk University of Technology, 11/12 Gabriela Narutowicza Street, 80-233 Gdańsk, Poland
2 shared publications - Michał Grzegorz Nowak
Université Libre de Bruxelles (ULB)
2 shared publications - Aleksandra Kuplińska
Department of Pharmaceutical Technology and Biochemistry, Gdańsk University of Technology
1 shared publication - Edyta Składanek
Department of Pharmaceutical Technology and Biochemistry, Gdańsk University of Technology
1 shared publication - Hira Zahoor Rajput
Department of Pharmaceutical Technology and Biochemistry, Gdańsk University of Technology
1 shared publication - Iwona Gabriel
Department of Pharmaceutical Technology and Biochemistry, Gdansk University of Technology, Gdansk, Poland
1 shared publication
Latest Publications
- Open Access
- 21 October 2026
- Published by Taylor & Francis in Journal of Enzyme Inhibition and Medicinal Chemistry
- Vol. 41 (1) , 2749883
Anticandidal activity of L-β-(isoxazolin-5-on-2-yl)-alanine due to the inhibition of O -acetyl-L-homoserine sulfhydrylase and cystathionine γ-synthase
Systemic mycoses, caused mainly in the immunocompromised patients by Candida spp. yeasts, especially C. albicans, are difficult to treat because of the small set of effective chemotherapeutics, eme...
- 21 October 2026
- Published by Taylor & Francis in Journal of Enzyme Inhibition and Medicinal Chemistry
- Vol. 41 (1) , 2749883
Open AccessAnticandidal activity of L-β-(isoxazolin-5-on-2-yl)-alanine due to the inhibition of O -acetyl-L-homoserine sulfhydrylase and cystathionine γ-synthase
Systemic mycoses, caused mainly in the immunocompromised patients by Candida spp. yeasts, especially C. albicans, are difficult to treat because of the small set of effective chemotherapeutics, eme...
- 1 December 2024
- Published by Bentham Science Publishers Ltd. in Current Medicinal Chemistry
- Vol. 31 (40) , 6614-6629
Rhodotorulic Acid and its Derivatives: Synthesis, Properties, and Applications
: Siderophores are low molecular weight compounds produced by microorganisms to scavenge iron in iron-deficient environments. Rhodotorulic acid, a natural hydroxamate siderophore, plays a vital role in iron acquisition for fungi and bacteria. As the simplest natural hydroxamate siderophore, it exhibits a high affinity for ferric ions, enabling it to form stable complexes that facilitate iron uptake and transport within microorganisms. This article provides a comprehensive analysis of this hydroxamate siderophore, rhodotorulic acid, its synthesis, physicochemical properties, and biological significance. It also explores its applications in antifungal and plant protection strategies. Insights into RA derivatives reveal distinct biological effects and applications with potential in various fields, from antioxidants to antifungals. Rhodotorulic acid and its derivatives show promise for novel therapies, plant protection strategies, and iron supplementation in agriculture. Understanding their properties could advance science and medicine with sustainable practices.
- 1 December 2024
- Published by Bentham Science Publishers Ltd. in Current Medicinal Chemistry
- Vol. 31 (40) , 6614-6629
Rhodotorulic Acid and its Derivatives: Synthesis, Properties, and Applications
: Siderophores are low molecular weight compounds produced by microorganisms to scavenge iron in iron-deficient environments. Rhodotorulic acid, a natural hydroxamate siderophore, plays a vital role in iron acquisition for fungi and bacteria. As the simplest natural hydroxamate siderophore, it exhibits a high affinity for ferric ions, enabling it to form stable complexes that facilitate iron uptake and transport within microorganisms. This article provides a comprehensive analysis of this hydroxamate siderophore, rhodotorulic acid, its synthesis, physicochemical properties, and biological significance. It also explores its applications in antifungal and plant protection strategies. Insights into RA derivatives reveal distinct biological effects and applications with potential in various fields, from antioxidants to antifungals. Rhodotorulic acid and its derivatives show promise for novel therapies, plant protection strategies, and iron supplementation in agriculture. Understanding their properties could advance science and medicine with sustainable practices.
- Open Access
- 19 November 2024
- Published by Wiley in Chemistry – A European Journal
- Vol. 31 (4) , e202403486
Trimethyl Lock Based Tools for Drug Delivery and Cell Imaging – Synthesis and Properties
Trimethyl lock (TML) systems have become increasingly important in medicinal and bioorganic chemistry, particularly for their roles in the targeted delivery of therapeutic agents and as integral components in fluorogenic probes for cellular imaging. The simplicity and efficiency of their synthesis have established TML systems as versatile platforms for the controlled release of active molecules under particular physiological conditions. This review consolidates recent advancements in the application of TML systems, with a focus on their use in drug delivery, cellular imaging, and other areas where precise molecular release is crucial. Additionally, we discuss the synthetic strategies employed to construct TML‐based conjugates, underscoring their potential to enhance the specificity and efficacy of bioactive compounds in various biomedical applications.
- 19 November 2024
- Published by Wiley in Chemistry – A European Journal
- Vol. 31 (4) , e202403486
Open AccessTrimethyl Lock Based Tools for Drug Delivery and Cell Imaging – Synthesis and Properties
Trimethyl lock (TML) systems have become increasingly important in medicinal and bioorganic chemistry, particularly for their roles in the targeted delivery of therapeutic agents and as integral components in fluorogenic probes for cellular imaging. The simplicity and efficiency of their synthesis have established TML systems as versatile platforms for the controlled release of active molecules under particular physiological conditions. This review consolidates recent advancements in the application of TML systems, with a focus on their use in drug delivery, cellular imaging, and other areas where precise molecular release is crucial. Additionally, we discuss the synthetic strategies employed to construct TML‐based conjugates, underscoring their potential to enhance the specificity and efficacy of bioactive compounds in various biomedical applications.