R. K. Ahalya

The aim and objective of the research are to develop an automated diagnosis system for the prediction of rheumatoid arthritis (RA) based on artificial intelligence (AI) and quantum computing for hand radiographs and thermal images. The hand radiographs and thermal images were segmented using a UNet++ model and color-based k-means clustering technique, respectively. The attributes from the segmented regions were generated using the Speeded-Up Robust Features (SURF) feature extractor and classification was performed using k-star and Hoeffding classifiers. For the ground truth and the predicted test image, the study utilizing UNet++ segmentation achieved a pixel-wise accuracy of 98.75%, an intersection over union (IoU) of 0.87, and a dice coefficient of 0.86, indicating a high level of similarity. The custom RA-X-ray thermal imaging (XTNet) surpassed all the models for the detection of RA with a classification accuracy of 90% and 93% for X-ray and thermal imaging modalities, respectively. Furthermore, the study employed quantum support vector machine (QSVM) as a quantum computing approach which yielded an accuracy of 93.75% and 87.5% for the detection of RA from hand X-ray and thermal images. In addition, vision transformer (ViT) was employed to classify RA which obtained an accuracy of 80% for hand X-rays and 90% for thermal images. Thus, depending on the performance measures, the RA-XTNet model can be used as an effective automated diagnostic method to diagnose RA accurately and rapidly in hand radiographs and thermal images.

The study’s primary objectives encompass the following: (i) To implement the object detection of ovarian follicles using you only look once (YOLO)v8 and subsequently segment the identified follicles using a hybrid fuzzy c-means-based active contour technique. (ii) To extract statistical features and evaluate the effectiveness of both machine learning (ML) and deep learning (DL) classifiers in detecting polycystic ovary syndrome (PCOS). The research involved a two different dataset in which dataset1 comprising both normal (N = 50) and PCOS (N = 50) subjects, dataset 2 consists of 100 normal and 100 PCOS affected subjects for classification. The YOLOv8 method was employed for follicle detection, whereas statistical features were derived using Gray-level co-occurrence matrices (GLCM). For PCOS classification, various ML models such as Random Forest (RF), k- star, and stochastic gradient descent (SGD) were employed. Additionally, pre-trained models such as MobileNet, ResNet152V2, and DenseNet121 and Vision transformer were applied for the categorization of PCOS and healthy controls. Furthermore, a custom model named Follicles Net (F-Net) was developed to enhance the performance and accuracy in PCOS classification. Remarkably, the F-Net model outperformed among all ML and DL classifiers, achieving an impressive classification accuracy of 95% for dataset1 and 97.5% for dataset2 respectively in detecting PCOS. Consequently, the custom F-Net model holds significant potential as an effective automated diagnostic tool for distinguishing between normal and PCOS.

Parkinson’s disease (PD) is a long-term neurological condition that causes severe neuronal degeneration in the motor cortex. Because of the constraints of medical applications determining the severity of PD, forecasting its development can be difficult. Recently research has focused on artificial intelligence to automatically diagnose PD from MRI images. The proposed study aims (a) to incorporate automated method for augmentation of the MRI images using the deep convolutional generative adversarial networks (DCGAN), (b) to perform feature extraction and classification by employing the pre-trained models such as VGG16, Xception, and InceptionV3 models, (c) to develop a hybrid model by fusing the InceptionV3 features and classification using QSVM model. A total of 60 real-time MRIs of normal ([ ] = 30) and PD ([ ] = 30) patients were included in this study. To increase the dataset, the proposed study employed the DCGAN approach. Thus, the dataset for this study was increased to 1000 (normal and PD) images. Automatic feature extraction and classification were performed utilizing different pre-trained models such as VGG16, Xception, and InceptionV3. Among the pre-trained models InceptionV3 architecture provided high accuracy of 74% compared to other models. The proposed work developed a hybrid model by fusing InceptionV3 features and a quantum support vector machine (QSVM) for the detection of PD and healthy groups. The proposed model attained a prediction accuracy of 87.5% and high precision of 95%, respectively. Additionally, the hybrid architecture provided high recall and F1-measure of 84% and 89%, respectively. The hybrid model provided lowest false negative and false positive of 4 and 1, respectively. Therefore, the hybrid model could be an effective diagnostic tool for the automated prediction of PD.