Neha Brahmane

This systematic review protocol introduces the rationale to investigate how well the Vojta approach works to improve respiratory function and lessen neuromuscular deficits in premature newborns. Innovative approaches like the Vojta technique may offer a possible therapeutic path for preterm newborns, who frequently suffer significant obstacles in their early development. We outline a rigorous methodology for this systematic review. A comprehensive search strategy will be implemented across various databases to identify relevant studies. This systematic review will encompass randomized controlled trials through electronic and manual searches. Electronic searches will be carried out in databases such as PubMed, Medline, Scopus, and Web of Science. The search will span articles published from 2000 to 2025; predefined eligibility criteria involve participants who were premature babies (those born before 37 weeks gestation). Exposure includes participants diagnosed with any other diagnosis that does not include NRDS. Outcome measures focus on oxygen saturation levels (SpO₂), arterial blood gas (ABG) analysis (e.g., PaO₂, PaCO₂, and pH), respiratory rate (breaths per minute), and lung compliance (static or dynamic) will all be used to quantify respiratory function. Two independent reviewers will conduct study selection, data extraction, and risk of bias assessment. The primary outcomes encompassing SpO₂, ABG, Ballard, and APGAR will be systematically analysed. Dissemination and ethics As no primary data will be collected, ethical approval is not required. The findings will be presented at relevant conferences and published in a peer-reviewed journal. Systematic review registration PROSPERO CRD420250643755.

Background: Neonatal respiratory distress syndrome (NRDS), a common and serious illness in preterm infants, is characterized by lung immaturity and inadequate surfactant production. Even though improvements in neonatal care have increased survival rates, optimizing supportive therapies such as physiotherapy is still essential to improve respiratory outcomes and overall recovery. Objective: This study aims to evaluate the effectiveness of physiotherapy therapies in enhancing respiratory function and clinical outcomes in neonates with NRDS. Methods: PRISMA-P (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols) guidelines will be followed for conducting a systematic review. Studies assessing the effects of physiotherapy therapies on newborns with NRDS, such as respiratory exercises, manual chest compressions, percussion, vibration, and postural drainage, high-frequency oscillation of the chest wall, cough stimulation, or suctioning will be included. A comprehensive search of electronic databases, including PubMed, Embase, CINAHL, and the Cochrane Library, to find pertinent observational studies, experimental studies, and randomized controlled trials, will be conducted. Important outcomes will be respiratory function metrics, oxygen saturation levels, length of mechanical ventilation, occurrence of problems, and overall newborn outcomes. Results: Exact numbers are not accessible at this time, as the review is hypothetical and has not yet been conducted. In order to inform clinical procedures and future studies, the results will contain data on respiratory improvement, intervention kinds, safety profiles, and the best times and frequencies for physical therapy in neonates with respiratory distress syndrome. Conclusions: This review will provide a comprehensive understanding of the role of physiotherapy in managing NRDS and its impact on clinical outcomes in neonates. The findings may guide clinical practice and inform future research on noninvasive strategies for improving neonatal respiratory care.

Introduction Bronchopulmonary dysplasia (BPD) is a common chronic lung disease that affects premature infants and is characterized by disrupted alveolar and vascular development. Pulmonary complications significantly affect morbidity and mortality rates in neonates with BPD. Aim This systematic review aimed to outline a protocol for investigating the effects of pulmonary complications in neonates diagnosed with BPD. Methods A comprehensive search strategy will be implemented across electronic databases, including PubMed, MEDLINE, Embase, and Cochrane Library. Eligible studies will include primary research articles reporting pulmonary complications, such as pulmonary hypertension, respiratory infections, ventilator-associated events, and airway abnormalities among neonates diagnosed with BPD. Two independent reviewers screened the titles, abstracts, and full text of the identified articles for eligibility. Data extraction will be conducted using a predefined form, including study characteristics, participant demographics, types of pulmonary complications, and relevant outcomes. The methodological quality of the included studies will be assessed using appropriate tools, such as the Cochrane Risk of Bias Tool for randomized controlled trials. Outcome measures The primary outcomes of interest will include the prevalence and incidence of pulmonary complications among neonates diagnosed with BPD. Secondary outcomes will encompass the impact of pulmonary complications on clinical outcomes, such as respiratory morbidity, mortality rates, length of hospital stay, and neurodevelopmental outcomes. Narrative synthesis will be employed to summarize the findings of the included studies, and where applicable, a meta-analysis will be conducted to quantify the effects of pulmonary complications on neonatal outcomes. Discussion This systematic review protocol outlines a rigorous methodology for investigating the effects of pulmonary complications in neonates with BPD. The findings of this review will provide valuable insights into the burden of pulmonary complications in this vulnerable population, and inform clinical practice and future research endeavors aimed at improving the care and management of neonates with BPD. Systematic Review Registration no. CRD42024524133