NDNiokhor Dione

Niokhor Dione

University of California, Berkeley
*This is an algorithmically generated author record based on publicly available information.
See Latest Publications
See Most Cited Publications
SciProfiles
Google Scholar

Current Organizations / Institutes

The organizations/institutes from the scholar's latest article

Research Subjects

Niokhor Dione has a total of 3 co-authors. Here are the top co-authors by number of shared publications:

Latest Publications

  • Website
    Google Scholar
    Open Access

    First Isolation and Genomic Characterization of Escherichia ruysiae in Togo from a Five-Year-Old Patient with Gastroenteritis and Bloody Diarrhea

    by Kossi Kabo, Niokhor Dione, Kodjovi D. Mlaga, Tchadjobo Tchacondo

    Escherichia ruysiae is a recently characterized species within the Escherichia genus, often misclassified as E. coli due to limitations in existing operating procedures and diagnostic databases. In this study, we report the first isolation and genomic characterization of E. ruysiae in Togo, from a five-year-old female patient who was hospitalized with gastroenteritis and bloody diarrhea and subsequently died after eight days. Biochemical tests and MALDI-TOF initially identified the microorganism as E. coli, but phylogenomic and Average Nucleotide Identity (ANI) analysis confirmed it to be E. ruysiae, Clade IV with enteroaggregative associated genes. Whole genome sequencing of the strain FK53-34 enables the identification of resistance genes, including blaEC-15, eptA, and pmrF. The virulence profile of the strain included, but was not limited to aap, aatABC, and senB genes, which may support its pathogenicity and virulence. Multilocus sequence typing (MLST) did not match any known sequence type, which is obvious for a newly characterized microorganism. This study highlights the critical need for enhanced diagnostic tools and surveillance systems to identify emerging pathogens, including Escherichia ruysiae.

  • Website
    Google Scholar
    Open Access

    First Genomic Characterization of Escherichia ruysiae Isolated from a Five-Year-Old Patient with Gastroenteritis and Bloody Diarrhea in Togo

    by Kossi Kabo, Niokhor Dione, Kodjovi D. Mlaga, Tchadjobo Tchacondo¹

    Escherichia ruysiae is a recently characterized species within the Escherichia genus, often misclassified as E. coli due to limitations in existing operating procedure and diagnostic databases. In this study, we report the first isolation and genomic characterization of E. ruysiae in Togo, from a five-year-old female patient who was hospitalized with gastro-enteritis and bloody diarrhea and subsequently died after eight days. Biochemical tests and MALDI-TOF initially identified the microorganism as E. coli, but phylogenomic and Average Nucleotide Identity (ANI) analysis confirmed it to be E. ruysiae, Clade IV with enteroaggregative associated genes. Whole genome sequencing of the strain FK53-34 enables the identification of resistance genes including blaPBP, blaampH, acrA, emrF, baeS et tolC and various aminoglycoside-modifying enzymes, blaEC-15, eptA and pmrF. The virulence profile of the strain included but not limited to, aap, aatABC, senB, prmF genes which support its pathogenicity and virulence. Multilocus sequence typing (MLST) did not match any known sequence type, which is obvious for a newly characterized mi-croorganism. This study highlights the critical need for enhanced diagnostic tools and surveillance systems to identify emerging pathogens, including Escherichia ruysiae

    Cited by 1