Yiwei Liu

Chlorpyrifos (CPF) poses severe environmental and health risks, driving the need for on-site monitoring tools. This study presents a novel dual-recognition colorimetric sensor for ultrasensitive detection of CPF by coimmobilizing molecularly imprinted polymers (MIPs) and aptamers onto bimetallic Fe,Zr-MOF composites. The resulting Fe,Zr-MOF/Apt/MIP hybrid synergistically merges the structural robustness of MIPs with the conformational specificity of aptamers, while also functioning as both a nanocarrier and a peroxidase mimic. Notably, CPF binding sterically hinders substrate diffusion to catalytic sites, enabling quantitative detection via dose-dependent inhibition of TMB oxidation. The optimized sensor exhibits exceptional performance: a broad linear range (1-120 ng mL^-1), ultralow detection limit (0.105 ng mL^-1), and high specificity against interferents. When validated with complex matrices (apples, pears, and cabbage), it achieved satisfactory recoveries (91.0-110.0%). This work establishes a field-deployable strategy for on-site pesticide monitoring in food and environmental safety.

Mycotoxins are produced by fungi and possess cytotoxic properties that cause extensive cellular damage. Mycotoxins pose a significant threat to the harvesting and storage of crops as well as potential carcinogenic, teratogenic, and mutagenic risks to humans. Currently, 400 mycotoxins have been identified and are threatening the safety of food, especially agricultural products. Therefore, it is important to develop timely, rapid, and accurate methods for the detection of mycotoxins to effectively monitor and assess risks in agricultural products. This review extensively introduces various advanced detection methods toward five common mycotoxins from 2016 to the present, including optical, chromatographic, electrochemical, and some combination methods. Most of the listed methods have good sensitivity, selectivity, and potential for application in various matrices. In particular, numerous reports have focused on the development of advanced sensing technologies for detecting mycotoxins. Sensors based on electrochemical and optical technologies can improve mycotoxin detection by designing novel materials and sensing mechanisms. With the further development of technology, the development of more effective, efficient, convenient, and environmentally friendly sensors and the use of artificial intelligence for data computation can further protect public health and ensure food safety.

Core–shell structured NiO@Ni–Ci/CC exhibits superior water oxidation activity, requiring 387 mV overpotential to drive 15 mA cm⁻² in 1.0 M K–Ci.