Perla Sofía Vera Hernández
Research Subjects
Perla Sofía Vera Hernández has a total of 7 co-authors. Here are the top co-authors by number of shared publications:
- Ana Gabriela Sierra Brozón
Female Pelvic Surgery Department, Doyenne High Quality and Multidisciplinary Treatment Center for Endometriosis, Mexico City, Mexico, Mexico
1 shared publication - Christian Silva-Rengifo
Doyenne Institute, High Quality Diagnosis for Deep Endometriosis and Advanced Pelvic Surgery, Mexico City, Mexico
1 shared publication - Fernando Heredia Muñoz
Departamento de Ginecología y Obstetricia, Facultad de Medicina, Universidad de Concepción, Concepción, Chile; Unidad de Ginecología Mínimamente invasiva y Robótica, Clínica Andes Salud Concepción, Concepción, Chile
1 shared publication - Jordanna Diniz Osaki
Núcleo Avançado de Endometriose E Robótica, Hospital DF Star, Brasília, Brasil
1 shared publication - Lucia Chaul
Hospital Angeles Clínica Londres, Mexico City, Mexico
1 shared publication - Ramiro Cabrera Carranco
Female Pelvic Surgery Department, Doyenne High Quality and Multidisciplinary Treatment Center for Endometriosis, Ciudad de México 06700, Mexico
1 shared publication
Latest Publications
- Open Access
- 2 March 2026
- Published by IntechOpen
Precision Medical Management of Endometriosis: Neuroimmune Pathophysiology, Pain Phenotyping and Emerging Target Therapies
Endometriosis is a chronic, estrogen-dependent inflammatory disease influenced by complex neuroimmune interactions and pain chronification mechanisms. Modern medical management is increasingly guided by a deeper understanding of neuroinflammation, peripheral and central sensitization, and immune dysregulation, moving beyond traditional hormonal suppression. This chapter will synthesize the latest evidence on precision medicine approaches, integrating pain phenotyping, molecular and inflammatory biomarkers, and mechanisms of treatment resistance. It will explore targeted pharmacologic strategies, including neuromodulators, selective progesterone receptor modulators, immunomodulatory and anti-fibrotic agents, as well as innovative non-hormonal therapies under investigation. Additionally, it will highlight research gaps and opportunities for translational applications. The aim is to provide a rigorous, mechanism-based framework for individualized, effective, and biologically informed medical treatment of endometriosis.
- 2 March 2026
- Published by IntechOpen
Open AccessPrecision Medical Management of Endometriosis: Neuroimmune Pathophysiology, Pain Phenotyping and Emerging Target Therapies
Endometriosis is a chronic, estrogen-dependent inflammatory disease influenced by complex neuroimmune interactions and pain chronification mechanisms. Modern medical management is increasingly guided by a deeper understanding of neuroinflammation, peripheral and central sensitization, and immune dysregulation, moving beyond traditional hormonal suppression. This chapter will synthesize the latest evidence on precision medicine approaches, integrating pain phenotyping, molecular and inflammatory biomarkers, and mechanisms of treatment resistance. It will explore targeted pharmacologic strategies, including neuromodulators, selective progesterone receptor modulators, immunomodulatory and anti-fibrotic agents, as well as innovative non-hormonal therapies under investigation. Additionally, it will highlight research gaps and opportunities for translational applications. The aim is to provide a rigorous, mechanism-based framework for individualized, effective, and biologically informed medical treatment of endometriosis.