Factors associated with death among hospitalized older adults with COVID-19 in Brazil
Authors:
- Luiz Hiroshi InoueLILuiz Hiroshi Inoue
- Wanessa Cristina BacconWBWanessa Cristina Baccon
- Francielle Renata Danielli Martins MarquesFMFrancielle Renata Danielli Martins Marques
- Maria Aparecida SalciMSMaria Aparecida Salci
- Vanessa Denardi Antoniassi BaldisseraVBVanessa Denardi Antoniassi Baldissera
- Stéfane Lele RossoniSRStéfane Lele Rossoni
- Lígia CarreiraLCLígia Carreira
Open Access
- 1 January 2026
- journal article
- Published by FapUNIFESP (SciELO) in Revista Latino-Americana de Enfermagem
- Vol. 34
Abstract
Objective: to analyze the factors associated with death among hospitalized older adults with COVID-19 in Brazil. Method: a cross-sectional study conducted using publicly available secondary data from hospitalized older adults who died from COVID-19. Odds ratios were obtained through the adjustment of a logistic regression model. Results: the analysis comprised 468,239 deaths of hospitalized older adults in Brazil. Some factors were associated with death, such as: age between 75 and 84 years (OR=1.77; 95% CI=1.74-1.79) and 85 years or older (OR=3.01; 95% CI=2.96-3.06); race/ethnicity White (OR=1.11; 95% CI=1.05-1.17), Indigenous (OR=1.54; 95% CI=1.34-1.76), Brown (OR=1.28; 95% CI=1.22-1.35), and Black (OR=1.48; 95% CI=1.39-1.57); male sex (OR=1.27; 95% CI=1.25-1.28); COVID-19 vaccination (OR=0.68; 95% CI=0.67-0.69); use of invasive ventilatory support (OR=19.54; 95% CI=19.14-19.95) and non-invasive ventilatory support (OR=1.78; 95% CI=1.75-1.80). Conclusion: an association was identified between age, sex, race/ethnicity, COVID-19 vaccination, and the use of ventilatory support with COVID-19-related death.Keywords
This publication has 24 references indexed in Scilit:
- COVID‐19 Vaccine Effectiveness Against Hospitalization in Older Adults, VEBIS Hospital Network, Europe, September 2024–May 2025Influenza and Other Respiratory Viruses, 2025
- Effectiveness of the BNT162b2 and mRNA-1273 JN.1-adapted vaccines against COVID-19-associated hospitalisation and death: a Danish, nationwide, register-based, cohort studyThe Lancet Infectious Diseases, 2025
- Frailty in severe COVID-19 survivors after ICU admission. A prospective and multicenter study in MexicoMedicina Intensiva (English Edition), 2024
- Prediction models for COVID-19 disease outcomesEmerging Microbes & Infections, 2024
- Evaluation of Waning of SARS-CoV-2 Vaccine–Induced ImmunityJAMA Network Open, 2023
- Predictors of COVID-19 related death in elderly patients hospitalized due to COVID-19 infection: a cross-sectional study in the west of IranJournal of Public Health, 2023
- COVID-19 and cellular senescenceNature Reviews Immunology, 2022
- Post-acute COVID and long-COVID among adults and older adults in the State of Paraná, Brazil: protocol for an ambispective cohort studyBMJ Open, 2022
- Structural biology of SARS-CoV-2 and implications for therapeutic developmentNature Reviews Microbiology, 2021
- Risk factors for severe and critically ill COVID‐19 patients: A reviewAllergy, 2020