Eren Güzeloğlu

Objectives: Peer bullying represent significant public health challenges with profound implications for adolescent psychosocial development. This study investigates the frequency of traditional and cyberbullying among adolescents, specifically examining how BMI and socioeconomic factors predict victimization risk and frequency. This study aimed to determine the frequency of peerbullying among school-aged children and adolescents and to examine the predictive impact of body mass index (BMI) and socioeconomic factors on victimization. Methods: A cross-sectional study was conducted with 330 Turkish adolescents aged 10–17 years of school-aged children and adolescents. Data were collected using the 9-item Child-Adolescent Bullying Scale (CABS-9) – Short Form along with a demographic information form. BMI was calculated based on height and weight measurements. Statistical analysis included regression models to determine the variance explained by BMI. Results: The prevalence of peer bullying was found to be 42.1 %, while cyberbullying prevalence was 12.7 %. Male gender, lower socioeconomic status, and younger age (specifically 4th-grade students) were identified as significant risk factors. BMI accounted for 17.5 % of the variance in bullying victimization (R ² =0.175), with overweight and obese participants reporting significantly higher victimization scores (19.12 ± 6.15) compared to their normal-weight peers (13.50 ± 3.85). Verbal bullying (mocking and ridiculing) was the most frequent (33.9 %). Conclusions: The findings indicate that bullying frequency in this sample exceeds global averages but aligns with regional trends in high- frequency areas. The significant predictive power of BMI suggests that physical appearance remains a primary catalyst for peer exclusion and mockery. These results underscore the urgent need for early-intervention programs, starting in primary school, that focus on body positivity, self-esteem enhancement, and the social integration of economically disadvantaged students.

Objective: This multicenter retrospective real-world data study aimed to evaluate whether the use of a preparation containing polyphenol, vitamin D3, vitamin C, and zinc in addition to antiviral therapy was associated with symptom duration and severity, time to fever resolution, and functional recovery in children diagnosed with influenza. Materials and Methods: This was a five-center, multicenter, retrospective, comparative real-world data analysis. A total of 128 patients aged 4–10 years with a clinical diagnosis of influenza were classified into a control group receiving antiviral therapy alone (n = 64) and a combined polyphenol group receiving, in addition to antiviral therapy, a preparation containing polyphenol, vitamin D3, vitamin C, and zinc (n = 64). Clinical data were obtained from electronic patient records and parent-reported information. Symptom severity (0–3 ordinal score), recovery time, and functional outcomes were assessed on Days 0, 3, 5, and 7. Continuous variables were compared using the independent-samples t test, categorical variables using the chi-square or Fisher exact test, and changes over time using a repeated-measures general linear model. Statistical significance was accepted as a two-sided p value of p > 0.05). During follow-up, all symptom scores improved more rapidly and markedly in the combined polyphenol group than in the control group. By Day 3, significant differences were observed between groups in fever, cough, rhinorrhea, sore throat, fatigue, general condition, and physical activity scores (p < 0.001 for all parameters). By Day 5, almost complete resolution of symptoms (score 0) was observed in the combined polyphenol group, whereas symptoms persisted to a substantial extent in the control group (p < 0.001). The time to fever resolution was significantly shorter in the combined polyphenol group (1.84 ± 0.72 days vs. 4.5 ± 1.36 days; p < 0.001). Similarly, time to return to school (3.21 ± 0.9 days vs. 5.8 ± 1.91 days; p < 0.001) and time for parents to return to work were significantly shorter in the combined polyphenol group (p < 0.001). The need for additional healthcare visits and antipyretic use was markedly lower in the combined polyphenol group (Day 3: 20.3% vs. 53.1%; Day 5: 0% vs. 15.6%; p < 0.001 for both comparisons). Repeated-measures analyses showed a significant time-by-group interaction, indicating that the reduction in symptom scores occurred more rapidly and prominently in the combined polyphenol group (p < 0.001). Treatment was generally well tolerated in the combined polyphenol group; no serious adverse events were reported, and parent-reported tolerability was high (9.39 ± 0.7). Conclusions: This multicenter retrospective real-world data study suggests that the use of a preparation containing polyphenol, vitamin D3, vitamin C, and zinc in addition to antiviral therapy was associated with shorter symptom duration, lower symptom severity scores, and faster functional recovery in children diagnosed with influenza. These findings suggest that this combination may represent a promising and well-tolerated adjunctive approach in the management of pediatric influenza.

Background: Artificial intelligence (AI) is increasingly integrated into healthcare, including pediatrics, offering new opportunities for diagnosis, management, and decision support. However, the effective implementation of AI depends largely on healthcare professionals’ knowledge, attitudes, and readiness to adopt these technologies. This study aimed to evaluate pediatricians’ general attitudes toward artificial intelligence and their level of readiness for medical AI in Istanbul, Türkiye at tertiary hospital. Distinct from previous research focusing primarily on medical students, this study investigates the AI readiness of practicing pediatricians within a major tertiary hospital in Istanbul, addressing a critical gap in professional clinical workforce assessment. Methods: This descriptive cross-sectional study was conducted between August 1 and November 1, 2025, at Prof. Dr. Cemil Taşcıoğlu City Hospital. A total of 130 pediatricians participated. Data were collected using a sociodemographic questionnaire, the GAAIS (General Attitudes toward Artificial Intelligence Scale), and the MAIRS-MS (Medical Artificial Intelligence Readiness Scale for Medical Students). The validity and reliability of scales in Turkish have been previously investigated in various studies. The internal consistency of the scales was excellent, with a Cronbach’s alpha coefficient of 0.972 in our study. Statistical analyses were performed using SPSS 27. Correlation, t-test, ANOVA, and non-parametric tests were applied where appropriate. Results: The mean age of participants was 37.47 ± 9.31 years, and 58.5% were female. The mean AI positive attitude score was 3.81 ± 0.74, and the negative attitude score was 2.83 ± 0.81. The total MAIRS-MS score was 74.97 ± 13.01, indicating a moderate-to-high level of AI readiness. Age was negatively correlated with AI positive attitude and total MAIRS score ( p < 0.05). Participants with ≥ 21 years of professional experience had significantly lower AI readiness and positive attitude scores than younger participants ( p < 0.05). A strong positive correlation was found between AI positive attitude and total MAIRS-MS score ( r = 0.764, p < 0.01). Multiple regression analysis revealed that “Ability” (β = 0.516, p < 0.001) and “Cognition” (β = 0.323, p < 0.001) factors were the strongest predictors of a positive attitude toward AI (R ² = 0.658). A strong positive correlation was found between AI positive attitude and total MAIRS-MS score ( r = 0.764, p < 0.01). These results suggest that clinical AI implementation must be accompanied by tailored institutional support and age-specific training to bridge the generational digital divide in pediatric care. Conclusion: Pediatricians generally demonstrated positive attitudes and moderate-to-high readiness for artificial intelligence in our study. However, advanced age and longer professional experience were associated with lower readiness levels. These findings highlight the need for a structured AI education and training program, especially targeting senior physicians, to ensure effective and ethical integration of AI into pediatric practice.

The disease characterized by the developmental and function disorders of T and B lymphocytes together with natural killer cells is called 'Severe combined immunodeficiency'. Due to the impairment of cellular and humoral immunity, opportunistic infections such as persistent diarrhea, recurrent pneumonia attacks, chronic sinusitis and oral candidiasis begin to be seen in the first 3 months, while cases left untreated lose their lives within the first 24 months. In this study, we present a 6-month-old male child with severe combined immunodeficiency presented with pneumonia, which is among the pediatric emergencies having a high morbidity and mortal results

Sleep is necessary for the psychological, physiological, and emotional growth of children and adolescents. Pediatric sleep disorders are common and sometimes overlooked by health professionals. Recent developments in screen time have led to more sleep-related problems among adolescents. Encouraging good sleep habits and limiting screen time in children is crucial for their health. Pediatricians have a responsibility to incorporate sleep hygiene advice and routine sleep checks into their practice to promote healthy child development. Heightened awareness, public health initiatives, and interdisciplinary collaboration are essential to tackle this pervasive problem effectively. This study is a narrative review of the literature on sleep disorders and sleep hygiene in children and adolescents. Relevant publications were identified through searches of PubMed, Scopus, and SciELO databases using the following keywords: "pediatric sleep disorders," "sleep hygiene children," "screen time sleep adolescents," "obstructive sleep apnea children," "parasomnias childhood," and "behavioral insomnia pediatric." Priority was given to publications from 2019 onwards; however, seminal studies published before this date were also included where appropriate. Articles were selected based on their relevance to the scope of the review. Editorials and opinion pieces without supporting data were excluded.

Background/Objectives: Group A Streptococcus (GAS) pharyngitis is a frequent cause of morbidity in pediatric populations, which requires timely identification to prevent complications such as acute rheumatic fever. Rapid antigen detection tests (RADTs) are practical alternatives to throat culture. This study evaluates the diagnostic performance of the RapidFor™ Strep A test. Methods: This prospective clinical study enrolled 389 pediatric patients aged < 18 years with symptoms suggestive of streptococcal pharyngitis. Two throat swabs were collected from each patient: one for rapid antigen testing with RapidFor™ Strep A and one for culture. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated. Results: Throat culture was positive in 95 of 389 patients (24.4%). The RapidFor™ Strep A test demonstrated a sensitivity of 98.95% (95% confidence interval [CI]: 94.28–99.81%) and a specificity of 96.26% (95% CI: 93.43–97.90%). The PPV was 89.52%, and the NPV was 99.65%. Agreement with culture was excellent (κ = 0.919); in particular, false-positive results accounted for 2.8% and false-negative results accounted for 1.05%. Fever was the strongest clinical indicator associated with positive results. Conclusions: The RapidFor™ Strep A test showed very high diagnostic accuracy compared with throat culture, including an excellent NPV (99.6%), which supports its reliability for ruling out GAS pharyngitis in pediatric settings. The test is an effective screening tool that facilitates timely antibiotic therapy.

Amaç: Bu çalışmada, rotavirüs antijen testi pozitif akut gastroenteritli 2–14 yaş çocuklarda ayaktan standart tedaviye Kolloidal Silisyum Dioksit eklenmesinin klinik seyir üzerine etkisini değerlendirmek amaçlandı. Kolloidal Silisyum DioksitGereç ve Yöntem: Rotavirüs pozitif ayaktan izlenen çocuklarda iki gruplu karşılaştırmalı analiz yapıldı (Standart tedavi: sıvı + çinko + probiyotik; Standart+ Kolloidal Silisyum Dioksit. Çalışma toplam 5 ayrı hastanede standart tedavi verilen 150 ve standart tedaviye ek olarak Kolloidal Silisyum Dioksit kullanan 150 Rotavirüs tanılı çocuk dahil edilidi. Çalışmamız çok merkezli, multisentrik ve iki grup karşılaştırmalı olarak planlandı. Çalışma Takip penceresi Gün 0–7 idi. Primer sonlanım ishalin düzelmesine kadar geçen süre olarak tanımlandı (ilk kez dışkı sayısı ≤3/gün ve Bristol ≤5 sağlanması). İkincil sonlanımlar toplam dışkı sayısı, dışkı tipi, dışkı kıvamı, ateş seyri, hastaneye başvuru, okul ve işgücü kaybı ve ürün güvenliği idi. Sürekli değişkenlerde uygun parametrik/parametrik olmayan testler; ikili değişkenlerde Fisher kesin testi; ishal düzelme için Kaplan-Meier ve log-rank testi kullanıldı (p

Necrotizing pneumonia is a rare complication of bacterial lung infections, and host factors and the virulence of the microorganism are effective in its emergence. The most common microorganisms involved in etiology are Staphylococcus aureus, Streptococcus pyogenes, Klebsiella pneumonia, Nocardia and Streptococcus pneumonia . Patients may present with high fever, rapidly progressing respiratory distress, cough, hemoptysis and rapid deterioration in radiological findings. Necrotizing pneumonia heals without sequelae in healthy children. However, in a small number of cases, it may be complicated by lung abscess, empyema, pneumatocele or bronchopleural fistula. A case of necrotizing pneumonia successfully treated with fibrinolytic therapy applied in the early period is presented here.