A.A. Bondar

Relevance. Recent-years research specifies the influence of body internal environmental factors on the development and maturity of hard dental tissues. The negative impact of which causes severe amelogenesis disorder, with the formation of immature enamel, the hypoplastic phenotype of different intensity. The timing of tooth eruption in humans has become unpredictable as the child development accelerates and new orofacial dysplastic phenomena appear or are inherited. Tooth eruption with localized or generalized hypomineralization is little studied. The study aims to compare the rate of dental enamel mineral component maturation in males and females of different ages by electron and atomic force microscopy.Materials and methods. The study involved 90 female and male subjects, aged 15-20, 21-30, 31-40 years. Impacted teeth 38 were extracted on medical grounds in all patients. The study analyzed the shape, packing and the 3D surface of enamel prisms using a Jeol JCM – 5700 scanning electron microscope and an NTEGRA Prima atomic force microscope according to Omsk State Medical University methods. The variation statistics methods processed the received data using standard packages Microsoft Excel 2008, Statistica 12.0.Results. The enamel prisms in females aged 15-20, 21-30 years are not closely spaced, compared to similar ages in the male group, as indicated by the distance between enamel prisms (15-20 years U = 9.3496, p = 0.0035 between males and females; 21-30 years U = 10.6949, p = 0.0018 between males and females). In women aged 15-20 and 21-30 years, the enamel prisms are chaotically organized: a 6-sided or 7-sided prism of larger size often squeezes a less mature 5-sided prism, providing the characteristic appearance of an immature prism with ugly outlines in various geometric shapes. In 31-40-year-old women, the enamel prisms are more densely spaced.Conclusion. There are local and total hypomineralised areas of the enamel prisms in females under 30 years old and in males under 20 years old.

Objective. It is necessary to characterize the state of the dentoalveolar system in case of connective tissue dysplasia at different person's life age periods. Materials and methods. The study involved 200 people with odontogenic pathology. They were diagnosed with connective tissue dysplasia (CTD). All of examinated were divided into 2 equal groups with CTD and without CTD, each into 5 equal subgroups of 30 people, according to age: 15-20, 21-30, 31-40, 41-50, 51-60 years. A comprehensive assessment of CTD determination was carried out using diagnostic tables, including non-syndromic forms, in accordance with the total value (+17 or more) of diagnostic coefficients, calculated using the Kullback criteria. Results. The study of phenotypic, facial signs and dysplastic stigmas in the mouth at different ages with connective tissue dysplasia revealed a close relationship of facial, dental and odontological signs at 15-20, 21-30 years old. The most common dysplastic stigmas at a young age are malocclusion, violation of the teeth shape and position. This scientific fact can be explained by the phenomenon of doubt. Doubt is the accumulation of parents and the emergence of new dysplastic phenomena in the maxillofacial area. At the same time, the presented changes in the mouth indicate a violation of the harmony and architectonics of the dentoalveolar apparatus, associated with the general processes of ossification and development of organs and tissues of the mouth, which occur in combination with large stigmas. Conclusions. A comprehensive examination of the maxillofacial region in patients with connective tissue dysplasia revealed a wide variety of dysplastic changes at 15-20, 21-30 years old: curvature of the spine, arachnodactyly, gothic palate, violation of bite, shape and position of teeth, the presence of diastemas, in contrast from groups 31-40, 41-50, 51-60 years old, where these signs were found in single observations. Age-related variability of the studied morphometric and odontological parameters of teeth 3.8, 4.8, showed a pronounced variability at 15-20, 21-30 years with connective tissue dysplasia.